Trends in cancer and heart failure related mortality in adult US population: A CDC WONDER database analysis from 1999 to 2020.

Autor: Qazi SU; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Hamid A; Division of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Ansari HUH; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Khouri MG; Division of Cardiology, Department of Medicine, Duke University, Durham, NC, USA., Anker MS; Department of Cardiology CBF German Heart Center Charité, DZHK, BCRT, University Medicine Berlin FU and HU, Berlin, Germany., Hall ME; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA., Anker SD; Department of Cardiology (CVK), Berlin Institute of Health Center for Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitäts medizin Berlin, Germany., Butler J; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA; Baylor Scott and White Research Institute, Dallas, Texas, USA., Khan MS; Baylor Scott and White Research Institute, Dallas, Texas, USA; Division of Cardiology, Baylor Scott and White The Heart Hospital, Plano, TX, USA; Department of Medicine, Baylor College of Medicine, Temple, TX, USA. Electronic address: shahzebkhan@gmail.com.
Jazyk: angličtina
Zdroj: American heart journal [Am Heart J] 2024 Dec; Vol. 278, pp. 170-180. Date of Electronic Publication: 2024 Sep 17.
DOI: 10.1016/j.ahj.2024.09.002
Abstrakt: Background: With the advent of novel chemotherapy, survival of patients with cancer has improved. However, people with cancer have an increased risk of heart failure (HF). Conversely, HF-related mortality may undermine survival among people with cancer. We aim to analyze the trends of mortality in people with HF and cancer in the adult US population.
Methods: We conducted an examination of death certificates sourced from the CDC WONDER (Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research) database, from the years 1999 to 2020. Mortality in adults with HF and cancer was assessed. Age-adjusted mortality rates (AAMRs) per 100,000 persons and annual percent change were reported.
Results: Between 1999 and 2020, 621,783 deaths occurred from HF in people with cancer. The AAMR declined from 16.4 in 1999 to 11.9 in 2017, after which an increase to 14.5 was observed in 2020. Men had consistently higher overall AAMR as compared to women (men = 18.1 vs women = 9.9). Similar AAMR was observed between non-Hispanic (NH) Blacks/African Americans (13.9) and NH Whites (13.3), with lower in American Indian/Alaska Native (9.6) and Hispanics (7.4). Asian/Pacific Islanders reported the lowest AAMR (5.7). The Midwestern region reported the highest AAMR (14.8). We observed the highest AAMR amongst the older population (61.4).
Conclusion: The mortality rates of people with HF and cancer are increasing in the adult U.S.
Population: This underscores the need for increased screening, aggressive management, and subsequent surveillance of people at risk or with manifested HF in people with cancer.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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