Establishing human microbial observatory programs in low- and middle-income countries.

Autor: Gordon JI; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.; The Newman Center for Human Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, Missouri, USA., Barratt MJ; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.; The Newman Center for Human Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, Missouri, USA., Hibberd MC; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.; The Newman Center for Human Gut Microbiome and Nutrition Research, Washington University School of Medicine, St. Louis, Missouri, USA., Rahman M; International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh., Ahmed T; International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Jazyk: angličtina
Zdroj: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2024 Oct; Vol. 1540 (1), pp. 13-20. Date of Electronic Publication: 2024 Sep 19.
DOI: 10.1111/nyas.15224
Abstrakt: Studies of the human microbiome are progressing rapidly but have largely focused on populations living in high-income countries. With increasing evidence that the microbiome contributes to the pathogenesis of diseases that affect infants, children, and adults in low- and middle-income countries (LMICs), and with profound and rapid ongoing changes occurring in our lifestyles and biosphere, understanding the origins of and developing microbiome-directed therapeutics for treating a number of global health challenges requires the development of programs for studying human microbial ecology in LMICs. Here, we discuss how the establishment of long-term human microbial observatory programs in selected LMICs could provide one timely approach.
(© 2024 The Author(s). Annals of the New York Academy of Sciences published by Wiley Periodicals LLC on behalf of The New York Academy of Sciences.)
Databáze: MEDLINE
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