Relationship between weight-adjusted-waist index and all-cause and cardiovascular mortality in individuals with type 2 diabetes.

Autor: Zhang TY; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Zhang ZM; Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Wang XN; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Kuang HY; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Xu Q; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Li HX; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Xu CY; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Zhao KQ; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Zhang C; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China., Hao M; Department of Endocrinology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Jazyk: angličtina
Zdroj: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Dec; Vol. 26 (12), pp. 5621-5629. Date of Electronic Publication: 2024 Sep 18.
DOI: 10.1111/dom.15929
Abstrakt: Aim: To investigate the relationship between the weight-adjusted-waist index (WWI) and all-cause mortality as well as cardiovascular mortality in individuals with type 2 diabetes.
Methods: We used data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018 and the UK Biobank database. Restricted cubic spline curves and Cox proportional hazards models were employed to assess hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause mortality.
Results: In the UK Biobank database, compared with the lowest WWI quartile, the HR for all-cause and cardiovascular death in the highest quartile was 1.846 (95% CI 1.687-2.019) and 2.118 (95% CI 1.783-2.517), respectively, in the fully adjusted model. In the NHANES database, compared with the lowest WWI quartile, the highest quartile had an HR of 1.727 (95% CI 1.378-2.163) for all-cause death and 1.719 (95% CI 1.139-2.595) for cardiovascular death in the fully adjusted model.
Conclusions: Our study indicates that WWI has a long-term synergistic negative impact on all-cause mortality and cardiovascular mortality in individuals with type 2 diabetes. The WWI is an independent predictor of mortality in individuals with type 2 diabetes.
(© 2024 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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