Global epidemiology, genotype distribution and coinfection rate of Human Aichi virus: A systematic review.

Autor: Abdelqader R; Department of Basic Medical Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, 13133, Jordan., Hasan H; University of Jordan, Amman, 11942, Jordan., Shuqair DA; Department of Basic Medical Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, 13133, Jordan., Zueter AM; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan. Electronic address: zeuterabdelRahman@gmail.com., Albakri KA; Faculty of Medicine, The Hashemite University, Zarqa, Jordan., Ghanem M; Mega Labs, Amman, Jordan.
Jazyk: angličtina
Zdroj: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2024 Sep 16. Date of Electronic Publication: 2024 Sep 16.
DOI: 10.1016/j.jiac.2024.09.012
Abstrakt: Background: Acute gastroenteritis is a major health concern for all age groups and accounts for more than 2.5 million deaths annually in children under five years old. Human Aichi virus causes acute gastroenteritis and is associated with foodborne outbreaks. Little is known about its pathogenicity, evolution, and geographical distribution.
Objective: This study aimed to describe the global seroprevalence of AiV-1 and its genotype distribution, track outbreaks, and estimate co-infection rates with other viral gastroenteritis.
Methods: A comprehensive systematic search of the epidemiological aspects of AiV-1 was conducted using peer-reviewed English original articles indexed in several scientific database libraries since its first detection in Japan until October 2022. A total of 55 published studies were included in the final analysis based on the inclusion criteria.
Result: The global prevalence of AiV-1 was 1.45 %. To date, nine AiV-1 outbreaks were reported following the first oyster-associated outbreak in Japan between 1987 and 1991. AiV-1 genotype A has a worldwide distribution, whereas genotypes B and C have a pattern of geo-localization. The gradual and significant increase of AiV-1 seroprevalence with age was reported in all studies. The most predominant viruses causing viral coinfection among AiV-1-infected patients were Norovirus (36.55 %), Rotavirus (18.91 %), and Sapovirus (15.13 %). Coinfections with Norovirus (p-value 0.003), Rotavirus (p = 0.007), and Human Astrovirus (p = 0.032) were significantly correlated with AiV-1 coinfection.
Conclusion: This was the first comprehensive systematic review of AiV-1. Although AiV-1 has a low global prevalence, it can be considered a health concern due to its association with childhood gastroenteritis.
Competing Interests: Declaration of competing interest The authors declare no conflict of interest.
(Copyright © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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