Problems in screening for gestational diabetes mellitus by measurement of casual blood glucose levels at 24-28 gestational weeks.

Autor: Tomimoto M; Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan., Tanimura K; Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan., Masuko N; Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan., Uchida A; Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan., Imafuku H; Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan., Deguchi M; Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan., Yamamoto A; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Hirota Y; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Ogawa W; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Terai Y; Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan.
Jazyk: angličtina
Zdroj: Journal of diabetes investigation [J Diabetes Investig] 2024 Sep 18. Date of Electronic Publication: 2024 Sep 18.
DOI: 10.1111/jdi.14310
Abstrakt: Aims/introduction: This study aimed to evaluate the problems in screening for gestational diabetes mellitus (GDM) by casual blood glucose (CBG) measurements at 24-28 gestational weeks.
Materials and Methods: Overall, 763 pregnant women who underwent the 50-g glucose challenge test (GCT) at 24-28 gestational weeks were enrolled. The preload blood glucose (0-h BG) level of 50-g GCT was considered as CBG.
Results: A total of 240 women with BG levels at 1-h after loading (1-h BG) on 50-g GCT ≥140 mg/dL underwent the 75-g oral glucose tolerance test, and 98 (40.8%) were diagnosed with GDM. Of the 99 women with GDM, 71 (71.7%) had 0-h BG on 50-g GCT <100 mg/dL.
Conclusions: This study, where pregnant women underwent both CBG and 50-g GCT simultaneously, showed that when CBG at 24-28 gestational weeks ≥100 mg/dL alone was used for screening GDM, many pregnant women with GDM were overlooked.
(© 2024 The Author(s). Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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