A brief history of the animals' scientific research, international rules and Brazilian regulations.

Autor: Ramos CLS; Universidade Federal do Piauí, Departamento de Biofísica e Fisiologia, Laboratório de Cancerologia Experimental (LabCancer), Campus Universitário Ministro Petrônio Portella, Ininga, 64049-550 Teresina, PI, Brazil., Beserra Filho JIA; Universidade Federal do Piauí, Departamento de Biofísica e Fisiologia, Laboratório de Cancerologia Experimental (LabCancer), Campus Universitário Ministro Petrônio Portella, Ininga, 64049-550 Teresina, PI, Brazil., Menezes DP; Universidade Federal do Piauí, Departamento de Biofísica e Fisiologia, Laboratório de Cancerologia Experimental (LabCancer), Campus Universitário Ministro Petrônio Portella, Ininga, 64049-550 Teresina, PI, Brazil., Ferreira PMP; Universidade Federal do Piauí, Departamento de Biofísica e Fisiologia, Laboratório de Cancerologia Experimental (LabCancer), Campus Universitário Ministro Petrônio Portella, Ininga, 64049-550 Teresina, PI, Brazil.
Jazyk: angličtina
Zdroj: Anais da Academia Brasileira de Ciencias [An Acad Bras Cienc] 2024 Sep 13; Vol. 96 (suppl 1), pp. e20231406. Date of Electronic Publication: 2024 Sep 13 (Print Publication: 2024).
DOI: 10.1590/0001-3765202420231406
Abstrakt: Several countries and non-governmental organizations have discussed the use of animals in industry and biomedical areas. This work shows the progression of animal' rights for scientific purposes in Brazil and how Brazilian Councils have advanced to follow worldwide regulations. Since the first rules about animals' usage in Ireland in 1635, the British Cruelty to Animals Act in 1876, and the Brazilian animal protection rules in 1924 and 1934, most worldwide actions culminated in the Universal Declaration of Animal Rights (1978). In 1979, the Brazilian Law 6.638 displayed directives for didactic-scientific practice of vivisection. In 2008, the Arouca Law 11.794 filled regulatory gaps and created the National Council for the Control of Animal Experimentation (CONCEA). In 2014, the CONCEA incorporated the 3R's philosophy and recognized substitute techniques, but only in 2023 it prohibited vertebrate animals in scientific research, development and control of personal hygiene products, cosmetics and perfumes. It is clear current Brazilian and international rules are unable to cover all aspects of animal wellbeing, even for regulations of commercial issues. Certainly, innovative tools, as organ-on-chip, in vitro techniques and bioinformatical advancements will provide a crucial animal welfare and new laws will minimize animal pain and distress, including for disregarded invertebrates.
Databáze: MEDLINE