Torsemide in the Management of Pulmonary Edema.

Autor: Vora A; Chest Physician, Department of Medicine, Vora Clinic, Mumbai, Maharashtra, India, Corresponding Author., Sharma A; Consultant Cardiologist, Department of Cardiology, Holy Spirit Hospital, Mumbai, Maharashtra, India., Sivakadaksham; Senior Consultant Cardiologist, Department of Cardiology, Siva Cardiac Care Centre, Chennai, Tamil Nadu, India., Sundar RH; Senior Interventional Cardiologist, Department of Cardiology, Madras Heart Centre, Chennai, Tamil Nadu, India., Mandal SC; Professor and HOD, Department of Cardiology, IPGME & R, and SSKM Hospital, Kolkata, West Bengal, India., Chatterjee N; Professor, Department of Medicine, WBMES, Kolkata, West Bengal, India., Agarwal A; Senior Consultant Interventional Cardiologist, Department of Cardiology, Jindal Institute of Medical Sciences, Hisar, Haryana, India., Bhatnagar MK; Professor and HOD, Department of Cardiology, Rajendra Prasad Government Medical College, Kangra, Himachal Pradesh, India., Gupta A; Medical Director and Chief Interventional Cardiologist, Department of Cardiology, Aashirwad Advanced Heart Lung & Critical Care Centre, Karnal, Haryana, India., Thaploo R; Senior Intervention Cardiologist, Department of Cardiology, Vivekananda Medical Institute, Kangra, Himachal Pradesh, India., Francis F; Medical Advisor, Medical Affairs, Cipla Ltd., Mumbai, Maharashtra, India., Mohanasundaram S; Country Head, Medical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.
Jazyk: angličtina
Zdroj: The Journal of the Association of Physicians of India [J Assoc Physicians India] 2024 Sep; Vol. 72 (9S), pp. 38-39.
DOI: 10.59556/japi.72.0677
Abstrakt: Pulmonary edema, either cardiogenic or noncardiogenic, is caused by fluid accumulation in the alveolar spaces. Cardiogenic pulmonary edema (CPE), one of the causes of congestive heart failure (CHF), is treated with loop diuretics. Torsemide and furosemide were found to be useful in the treatment of CHF-associated pulmonary edema due to their ability to lower pulmonary capillary pressure and left ventricular end-diastolic pressure, respectively. Pharmacological features of torsemide, such as greater bioavailability, higher absorption rate, and efficacy, make it a better alternative for treating pulmonary edema than the regularly used loop diuretic, furosemide. Torsemide administered intravenously was found to be both efficacious and well tolerated in CPE. However, more research is needed to determine its usefulness in non-CPE.
(© Journal of the Association of Physicians of India 2024.)
Databáze: MEDLINE