Large Vessel Vasculitis in a Patient Receiving G-CSF: A Possible Differential for Fever of Unknown Origin.

Autor: Mahdi RA; Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Krishnaraju VS; Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Mittal BR; Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Singh H; Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Kumar R; Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Prakash G; Department of Clinical Hematology and Medical Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Jazyk: angličtina
Zdroj: Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India [Indian J Nucl Med] 2024 May-Jun; Vol. 39 (3), pp. 224-226. Date of Electronic Publication: 2024 Aug 17.
DOI: 10.4103/ijnm.ijnm_138_23
Abstrakt: Large vessel vasculitis is a known but rare side effect of granulocyte colony-stimulating factor (G-CSF) therapy. We report a case of adenocarcinoma lung with pleural infiltration and mediastinal lymphadenopathy, who was treated with neoadjuvant chemotherapy and pegylated G-CSF. After three cycles, he developed a fever. He underwent F-18 fludeoxyglucose (FDG) positron emission tomography computed tomography for fever of unkwnown origin evaluation, which revealed a response to chemotherapy along with the appearance of FDG avid mural thickening in a few large arteries, suggesting a diagnosis of G-CSF-induced large vessel vasculitis.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2024 Indian Journal of Nuclear Medicine.)
Databáze: MEDLINE