Meningeal sporotrichosis in an immunocompetent host: A case report.

Autor:	Ribeiro VT; Departament of Neurology, Santa Casa de Belo Horizonte Hospital, Belo Horizonte (MG), Brazil., Caligiorne RB; Faculdade Santa Casa BH, Programa de Pós-graduação Stricto Sensu, Belo Horizonte (MG), Brazil., Martins AP; Departament of Neurology, Santa Casa de Belo Horizonte Hospital, Belo Horizonte (MG), Brazil., Gomes Neto AP; Departament of Neurology, Santa Casa de Belo Horizonte Hospital, Belo Horizonte (MG), Brazil., Christo PP; Departament of Neurology, Santa Casa de Belo Horizonte Hospital, Belo Horizonte (MG), Brazil.; Faculdade Santa Casa BH, Programa de Pós-graduação Stricto Sensu, Belo Horizonte (MG), Brazil.
Jazyk:	angličtina
Zdroj:	Medical mycology case reports [Med Mycol Case Rep] 2024 Aug 28; Vol. 45, pp. 100665. Date of Electronic Publication: 2024 Aug 28 (Print Publication: 2024).
DOI:	10.1016/j.mmcr.2024.100665
Abstrakt:	A 78-year-old woman presented to hospital with altered mental status. Hyponatremia was diagnosed and treated. She maintained mental confusion despite normal sodium. No headache, fever or focal signs were present. CSF analysis showed chronic meningitis; MRI demonstrated basilar enhancement. She was empirically treated for tuberculosis, with no improvement. PCR for Sporothrix in the CSF was positive. After treatment with Amphotericin followed by oral itraconazole, she completely recovered her cognitive abilities. Follow-up CSF was normal. This report illustrates the need to consider sporotrichosis in the differential diagnosis of chronic meningitis in immunocompetent, and the importance of PCR as a diagnostic tool. (© 2024 The Authors. Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu