Secondary prevention and extreme cardiovascular risk evaluation (SEVERE-0): Prevalence of extreme cardiovascular risk in cardiological rehabilitation patients and its impact on functional improvement.

Autor: Tognola C; Cardiology IV, 'A.De Gasperis' Department, Ospedale Niguarda Ca' Granda, Milan, Italy., Myriam Intravaia RC; Cardiology IV, 'A.De Gasperis' Department, Ospedale Niguarda Ca' Granda, Milan, Italy., Senini E; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Pezzoli S; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Riccio A; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Gualini E; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Fabbri S; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Bellantonio V; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Politi F; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Campana M; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Fucile I; Cardiac Rehabilitation Unit Federico II University Hospital and Department of Advanced Biomedical Science, Federico II University of Naples, Italy., Mancusi C; Cardiac Rehabilitation Unit Federico II University Hospital and Department of Advanced Biomedical Science, Federico II University of Naples, Italy., Golia E; University of Campania 'L. Vanvitelli', Naples, Italy - Division of Cardiology, AORN S. Anna e S. Sebastiano, Caserta, Italy., Cesaro A; University of Campania 'L. Vanvitelli', Naples, Italy - Division of Cardiology, AORN S. Anna e S. Sebastiano, Caserta, Italy., De Luca N; Cardiac Rehabilitation Unit Federico II University Hospital and Department of Advanced Biomedical Science, Federico II University of Naples, Italy., Calabrò P; University of Campania 'L. Vanvitelli', Naples, Italy - Division of Cardiology, AORN S. Anna e S. Sebastiano, Caserta, Italy., Giannattasio C; Cardiology IV, 'A.De Gasperis' Department, Ospedale Niguarda Ca' Granda, Milan, Italy; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Maloberti A; Cardiology IV, 'A.De Gasperis' Department, Ospedale Niguarda Ca' Granda, Milan, Italy; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy. Electronic address: alessandro.maloberti@ospedaleniguarda.it.
Jazyk: angličtina
Zdroj: Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2024 Aug 10. Date of Electronic Publication: 2024 Aug 10.
DOI: 10.1016/j.numecd.2024.08.006
Abstrakt: Background and Aims: Patients with recent Acute Coronary Syndrome (ACS) or Chronic Coronary Syndrome (CCS) are all at very high CardioVascular (CV) risk. However, some of them are more likely to experience recurrent cardiovascular events (i.e extreme CV risk). A definition of which patients should be included in this category has been recently proposed by the European Society of Cardiology but data on its prevalence are still lacking, especially in the context of Cardiac Rehabilitation (CR). Furthermore, if this condition had an impact on the CR related functional improvement is not known. Our study has been designed to answer to both these questions.
Methods and Results: The study included 938 ACS/CCS patients who attended the CR program at the Niguarda Hospital (Milan). Extreme CV patients were defined as the presence of a previous CV events within 2 years or the presence of peripheral arteriopathy or the presence of a multivessel coronary involvement. Functional improvement was evaluated through 6-Minute Walking Test (6-MWT). As many as 26.9% of the patients had an extreme CV risk. They were older (67.8 ± 10.4 vs 64.1 ± 11.1 years; p ≤ 0.001), had a higher prevalence of CV risk factors and comorbidities and had a lower functional improvement during CR (102.9 ± 68.6 vs 138.1 ± 86.5 m; p ≤ 0.001). Extreme CV risk present a significant association with the 6-MWT results at multivariate analysis.
Conclusion: Extreme CV risk is a very frequent condition among patients with ACS/CCS reaching the prevalence of 26.9%. Furthermore, being at extreme CV risk adversely affects the patient's functional improvement obtained during CR.
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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