Lipid-Laden Floret-Like Multinucleated Giant Cells: A Novel Histopathologic Observation in Rhinophyma.

Autor:	Daruish M; Department of Dermatopathology, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom ; and., Patalay R; Dermatological Surgery and Laser Unit (DSLU), St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom ., Calonje E; Department of Dermatopathology, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom ; and., Stefanato CM; Department of Dermatopathology, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom ; and.
Jazyk:	angličtina
Zdroj:	The American Journal of dermatopathology [Am J Dermatopathol] 2024 Nov 01; Vol. 46 (11), pp. 746-750. Date of Electronic Publication: 2024 Sep 17.
DOI:	10.1097/DAD.0000000000002834
Abstrakt:	Abstract: Rhinophyma is the advanced stage of rosacea and manifests clinically with disfigurement of the nose. The histopathology has been classified into classical and severe types. We studied the clinicopathological characteristics of 8 cases with the diagnosis of rhinophyma. In 5 of 9 specimens, floret-like multinucleated giant cells containing lipid were identified. This finding, to the best of our knowledge, has not been previously described. Competing Interests: The authors declare no conflicts of interest. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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