Development of the Pancreatic Ducts and Their Contribution to Organogenesis.
| Autor: | Dale DJ; Department of Biology, Indiana University-Indianapolis, Indianapolis, IN, USA., Rutan CD; Department of Biology, Indiana University-Indianapolis, Indianapolis, IN, USA., Mastracci TL; Department of Biology, Indiana University-Indianapolis, Indianapolis, IN, USA. tmastrac@iu.edu.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA. tmastrac@iu.edu.; Center for Diabetes and Metabolic Disease, Indiana University School of Medicine, Indianapolis, IN, USA. tmastrac@iu.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Advances in anatomy, embryology, and cell biology [Adv Anat Embryol Cell Biol] 2024; Vol. 239, pp. 31-55. |
| DOI: | 10.1007/978-3-031-62232-8_2 |
| Abstrakt: | The pancreas is a dual-function organ, with exocrine cells that aid in digestion and endocrine cells that regulate glucose homeostasis. These cell types share common progenitors and arise from the embryonic ducts. Early signaling events in the embryonic ducts shape the neonatal, adolescent, and adult exocrine and endocrine pancreas. This chapter discusses recent advances in the tools used to study the ducts and our current understanding of how ductal development contributes to pancreatic organogenesis. (© 2024. The Author(s), under exclusive license to Springer Nature Switzerland AG.) |
| Databáze: | MEDLINE |
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