Physical Characteristics, Clinical Application, and Side Effects of Viscoelastics in Ophthalmology.

Autor: Mohammadpour M; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Asadigandomani H; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.; Department of Ophthalmology, School of Medicine, Tehran University of Medical Science, Tehran, Iran., Aminizade M; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Raeisi S; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Jazyk: angličtina
Zdroj: Journal of current ophthalmology [J Curr Ophthalmol] 2024 Aug 10; Vol. 35 (4), pp. 313-319. Date of Electronic Publication: 2024 Aug 10 (Print Publication: 2023).
DOI: 10.4103/joco.joco_178_23
Abstrakt: Purpose: To explain the physical properties of ophthalmic viscoelastic devices (OVDs), covering their structural units, optimal features, existing viscoelastic materials, clinical applications, and potential side effects.
Methods: This is a narrative review on the OVDs. A literature review was conducted in PubMed, Google Scholar, and Scopus databases. Studies that investigated physical characteristics, clinical applications, OVD commercial products, and their complications were included.
Results: We included 42 articles from 2010 and discussed physical characteristics, properties of a desirable OVD, structural units of common OVDs, OVD commercial products, clinical applications, and also complications of OVDs.
Conclusions: Today, viscoelastics hold a distinct and crucial role in intraocular surgery due to their remarkable properties. These materials safeguard the endothelium and epithelium, uphold anterior chamber depth, manage intraocular bleeding, ease tissue handling, and aid intraocular lens placement. Currently, the American market features 12 prevalent viscoelastic types, including 7 sodium hyaluronate derivatives (Healon, Healon-Greater Viscosity, Healon-5, Amvisc, Amvisc Plus, Advanced Medical Optics Vitrax, and Provisc), 2 hydroxypropyl methylcellulose 2% derivatives (OcuCoat and Cellugel), and 3 combinations of sodium hyaluronate and chondroitin sulfate (Viscoat, DisCoVisc, and DuoVisc). Despite the introduction of new viscoelastic materials annually, no single material encompasses all desired properties. Surgeons must select and employ suitable viscoelastics based on surgical conditions and patient requirements. Advancements in material development and understanding of physical properties and clinical applications continue to refine viscoelastic selection.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2024 Journal of Current Ophthalmology.)
Databáze: MEDLINE
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