Polymyositis and Severe Rhabdomyolysis in the Context of Influenza and COVID-19 Vaccination: A Case Report.

Autor:	Ghiletchi A; Internal Medicine, Centro Hospitalar de Lisboa Central, Lisbon, PRT., Leão R; Internal Medicine, NOVA Medical School, Lisbon, PRT.; Internal Medicine, Centro Hospitalar de Lisboa Central, Lisbon, PRT., Coelho C; Internal Medicine, Centro Hospitalar de Lisboa Central, Lisbon, PRT., Ferreira I; Internal Medicine, Centro Hospitalar de Lisboa Central, Lisbon, PRT., Bernardino R; Internal Medicine, Centro Hospitalar de Lisboa Central, Lisbon, PRT.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Aug 15; Vol. 16 (8), pp. e66957. Date of Electronic Publication: 2024 Aug 15 (Print Publication: 2024).
DOI:	10.7759/cureus.66957
Abstrakt:	Rhabdomyolysis is characterized by muscle breakdown and the release of muscle enzymes into the bloodstream, which can lead to acute kidney injury (AKI) and electrolyte imbalances. This case report details a 52-year-old male who developed severe rhabdomyolysis and polymyositis following influenza and SARS-COV-2 vaccinations. Presenting with severe muscle pain and elevated creatine kinase (CK) levels, the patient's condition was managed with aggressive hydration and supportive care, resulting in significant recovery. While vaccine-related adverse effects such as myositis and rhabdomyolysis are rare, this case underscores the need for vigilance in monitoring post-vaccination complications and highlights the importance of recognizing and promptly treating vaccine-associated inflammatory myopathies to prevent severe complications. The findings contribute to the growing body of literature on vaccine-induced myopathies and emphasize the necessity of a multidisciplinary approach in managing such complex cases. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Ghiletchi et al.)
Databáze:	MEDLINE
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