Feasibility and safety of EUS-guided biliary drainage in inexperienced centers: a multicenter study in southwest Japan.

Autor: Koga T; Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Ishida Y; Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Hashigo S; Department of Gastroenterology, Kumamoto University Hospital, Kumamoto, Japan., Shimokawa Y; Department of Gastroenterology, Kitakyushu Municipal Medical Center, Fukuoka, Japan., Harima H; Department of Gastroenterology, Saiseikai Shimonoseki General Hospital, Yamaguchi, Japan., Okamoto K; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan., Ohno A; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Miyagahara T; Department of Gastroenterology, National Hospital Organization Beppu Medical Center, Oita, Japan., Fujita T; Department of Gastroenterology, Kagoshima Kouseiren Hospital, Kagoshima, Japan., Fukuchi S; Department of Gastroenterology, Oita City Medical Association Almeida Memorial Hospital, Oita, Japan., Takahashi K; Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Taguchi H; Department of Gastroenterology, Imamura General Hospital, Kagoshima, Japan., Araki N; Department of Gastroenterology, Fujimoto General Hospital, Miyazaki, Japan., Ohtsuka Y; Department of Gastroenterology, Oita Medical Center, Oita, Japan., Uekitani T; Department of Gastroenterology, Tokuyama Central Hospital, Yamaguchi, Japan., Tsuneyoshi K; Department of Gastroenterology Izumi General Medical Center, Kagoshima, Japan., Akiyama T; Division of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan., Ishigaki N; Department of Gastroenterology, Saiseikai Yamaguchi General Hospital, Yamaguchi, Japan., Maruo T; Department of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, Japan., Saito H; Department of Gastroenterology, Kumamoto City Hospital, Kumamoto, Japan., Ihara R; Department of Pancreatology, Kyushu Central Hospital, Fukuoka, Japan., Yamasuji A; Department of Gastroenterology, Ikeda Hospital, Kagoshima, Japan., Oe S; Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Fukuoka, Japan., Yoshinari M; Department of Gastroenterology, Kumamoto University Hospital, Kumamoto, Japan., Sagami R; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita, Japan., Fujimori N; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Fukuda Y; Department of Gastroenterology, Kagoshima Kouseiren Hospital, Kagoshima, Japan., Ozawa E; Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Jikuya K; Department of Gastroenterology, Imamura General Hospital, Kagoshima, Japan., Shinohara H; Department of Gastroenterology, Fujimoto General Hospital, Miyazaki, Japan., Sen-Yo M; Department of Gastroenterology, Tokuyama Central Hospital, Yamaguchi, Japan., Ueki T; Department of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, Japan., Tsuchiya N; Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Kitaguchi T; Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Matsumoto K; Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Fukuyama M; Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Hirai F; Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Jazyk: angličtina
Zdroj: Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Sep 13. Date of Electronic Publication: 2024 Sep 13.
DOI: 10.1016/j.gie.2024.09.014
Abstrakt: Background and Aims: EUS-guided biliary drainage (EUS-BD) has shown promising procedural outcomes in high-volume centers. Although inferior procedural outcomes were reported in inexperienced centers during the early days of EUS-BD, the current outcomes are unknown. This study aimed to clarify the feasibility and safety of EUS-BD in centers that recently introduced EUS-BD.
Methods: This multicenter retrospective study was conducted at 22 centers that introduced EUS-BD between 2017 and 2022. A maximum of 20 initial EUS-BD cases at each center were evaluated. The clinical outcomes and experience of 84 endoscopists who performed these procedures were examined. Primary outcomes were the rate of technical success and adverse events (AEs), whereas secondary outcomes were risk factors associated with technical failure and procedure-related AEs.
Results: Two hundred fifty-five patients were enrolled. The technical success rate was 91.4% (233/255). Among 22 technical failure cases, guidewire manipulation failure was the most common cause (n = 12) followed by tract dilation failure (n = 5). The AE rate was 10.2% (26/255). Multivariate analysis identified a puncture target diameter of <5 mm (odds ratio, 3.719; 95% CI, 1.415-9.776; P = .008) and moderate ascites extending to the liver surface (odds ratio, 3.25; 95% CI, 1.195-8.653; P = .021) as independent risk factors for technical failure and procedure-related AEs, respectively. Endoscopists' procedural experience was not a risk factor for technical failure or procedure-related AEs.
Conclusions: The feasibility and safety of EUS-BD were maintained during the induction phase at inexperienced centers. These data will be helpful to better understand the current status of EUS-BD. (Clinical trial registration number: UMIN 000053615.).
Competing Interests: Disclosure All authors disclosed no financial relationships.
(Copyright © 2024 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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