Exploring the Geroprotective Potential of Nutraceuticals.

Autor: Rivero-Segura NA; Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Mexico City 10200, Mexico., Zepeda-Arzate EA; Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Mexico City 10200, Mexico., Castillo-Vazquez SK; Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Mexico City 10200, Mexico.; Posgrado en Ciencias Biológicas, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico., Fleischmann-delaParra P; Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Mexico City 10200, Mexico., Hernández-Pineda J; Departamento de Infectología e Inmunología, Instituto Nacional de Perinatología, SSA, Mexico City 11000, Mexico., Flores-Soto E; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Avenida Universidad No. 3000, Alcaldía de Coyoacán, Mexico City 04510, Mexico., García-delaTorre P; Unidad de Investigación Epidemiológica y en Servicios de Salud, Área Envejecimiento, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico., Estrella-Parra EA; Laboratorio de Fitoquímica, UBIPRO, FES-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla de Baz 54090, Mexico., Gomez-Verjan JC; Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Mexico City 10200, Mexico.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2024 Aug 24; Vol. 16 (17). Date of Electronic Publication: 2024 Aug 24.
DOI: 10.3390/nu16172835
Abstrakt: Aging is the result of the accumulation of a wide variety of molecular and cellular damages over time, meaning that "the more damage we accumulate, the higher the possibility to develop age-related diseases". Therefore, to reduce the incidence of such diseases and improve human health, it becomes important to find ways to combat such damage. In this sense, geroprotectors have been suggested as molecules that could slow down or prevent age-related diseases. On the other hand, nutraceuticals are another set of compounds that align with the need to prevent diseases and promote health since they are biologically active molecules (occurring naturally in food) that, apart from having a nutritional role, have preventive properties, such as antioxidant, anti-inflammatory and antitumoral, just to mention a few. Therefore, in the present review using the specialized databases Scopus and PubMed we collected information from articles published from 2010 to 2023 in order to describe the role of nutraceuticals during the aging process and, given their role in targeting the hallmarks of aging, we suggest that they are potential geroprotectors that could be consumed as part of our regular diet or administered additionally as nutritional supplements.
Databáze: MEDLINE