Understanding Macrophage Interaction with Antimony-Doped Tin Oxide Plasmonic Nanoparticles.

Autor:	Balitskii O; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland.; Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada., Ivasiv V; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland.; CQUM-Centre of Chemistry, Chemistry Department, University of Minho, R. da Universidade, 4710-057 Braga, Portugal., Porteiro-Figueiras M; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland., Yajan P; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland., Witzig M; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland., Moreno-Echeverri AM; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland., Muñetón Díaz J; Department of Physics, University of Fribourg, 1700 Fribourg, Switzerland., Rothen-Rutishauser B; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland., Petri-Fink A; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland.; Department of Chemistry, University of Fribourg, Chemin du Musée 9, 1700 Fribourg, Switzerland., Keshavan S; Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland.
Jazyk:	angličtina
Zdroj:	Cells [Cells] 2024 Sep 01; Vol. 13 (17). Date of Electronic Publication: 2024 Sep 01.
DOI:	10.3390/cells13171468
Abstrakt:	Antimony-doped tin oxide nanoparticles (ATO NPs) have emerged as a promising tool in biomedical applications, namely robust photothermal effects upon near-infrared (NIR) light exposure, enabling controlled thermal dynamics to induce spatial cell death. This study investigated the interplay between ATO NPs and macrophages, understanding cellular uptake and cytokine release. ATO NPs demonstrated biocompatibility with no impact on macrophage viability and cytokine secretion. These findings highlight the potential of ATO NPs for inducing targeted cell death in cancer treatments, leveraging their feasibility, unique NIR properties, and safe interactions with immune cells. ATO NPs offer a transformative platform with significant potential for future biomedical applications by combining photothermal capabilities and biocompatibility.
Databáze:	MEDLINE
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