| Autor: |
Marsh RR, Lambersten CJ, Schwartz DM, Clark JM, Wetmore RF |
| Jazyk: |
angličtina |
| Zdroj: |
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 1985 Jun; Vol. 93 (3), pp. 390-3. |
| DOI: |
10.1177/019459988509300319 |
| Abstrakt: |
The therapeutic value of high partial pressures of oxygen is limited by the toxicity of oxygen. Pulmonary damage, visual impairment, and convulsions are known hazards during hyperoxic exposure, but dose-effect relationships have not been quantified for specific organs or functions. As part of an integrated study of organ oxygen tolerance in man (Predictive Study V of the Institute for Environmental Medicine), auditory and vestibular function was evaluated in man before, during, and after exposure to 100% oxygen at 3 atmospheres absolute pressure for 2 to 3.5 hours. No alterations in hearing or equilibrium were detected, suggesting that ototoxicity is not a factor that would limit exposure under these conditions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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