Greenness Exposure and Mortality Risk in a Cardio-Oncologic Population.

Autor:	Ashri S; Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical & Health Sciences, Tel Aviv University, Israel., Cohen G; Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical & Health Sciences, Tel Aviv University, Israel., Zadok OIB; Department of Cardiology, Rabin Medical Center (Beilinson and Hasharon Hospitals), Israel., Moran M; School of Public Health, University of Haifa, Israel., Broday DM; Technion Center of Excellence in Exposure Science and Environmental Health, Technion Israel Institute of Technology, Israel., Steinberg DM; Department of Statistics and Operations Research, Tel Aviv University, Israel., Keinan-Boker L; School of Public Health, University of Haifa, Israel.; Israel Center for Disease Control, Israel Ministry of Health, Israel., Witberg G; Department of Cardiology, Rabin Medical Center (Beilinson and Hasharon Hospitals), Israel., Bental T; Department of Cardiology, Rabin Medical Center (Beilinson and Hasharon Hospitals), Israel., Golan L; Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical & Health Sciences, Tel Aviv University, Israel., Shafran I; Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical & Health Sciences, Tel Aviv University, Israel., Kornowski R; Department of Cardiology, Rabin Medical Center (Beilinson and Hasharon Hospitals), Israel., Gerber Y; Department of Epidemiology and Preventive Medicine, School of Public Health, Faculty of Medical & Health Sciences, Tel Aviv University, Israel.
Jazyk:	angličtina
Zdroj:	European heart journal. Quality of care & clinical outcomes [Eur Heart J Qual Care Clin Outcomes] 2024 Sep 13. Date of Electronic Publication: 2024 Sep 13.
DOI:	10.1093/ehjqcco/qcae079
Abstrakt:	Background and Aims: Knowledge is lacking on the relationship between greenness and mortality in cancer survivors who experience coronary artery disease (CAD), a cardio-oncologic population. We aimed to investigate the association between residential greenness exposure and all-cause mortality in a cardio-oncologic population. Methods: Cancer survivors undergoing percutaneous coronary intervention at the Rabin Medical Center in Israel between 2004 and 2014 were included in the study. Clinical data were collected from medical records during index hospitalization and from the Israeli National Cancer Registry. Residential greenness was estimated by the normalized difference vegetation index (NDVI), a satellite-based index derived from Landsat imagery at a 30-meter spatial resolution, with larger values indicating higher levels of vegetative density (ranging between -1 to 1). Mortality follow-up data were obtained through the end of 2021. Cox models were used to assess the hazard ratios (HRs) for all-cause mortality per 1SD increase in NDVI. Results: Among 1,331 patients analyzed [mean (SD) age, 75.6 (10.2) years, 373 (28%) females], the mean (SD) NDVI within a 300-meter radius was 0.12 (0.03). During a median follow-up period of 12.0 (IQR 9.2-14.7) years, 883 (66%) participants died. After adjustment for potential confounding factors, including residential socioeconomic status, air pollution, and smoking, NDVI was inversely associated with mortality hazard [HR (95% CI) = 0.93 (0.86, 0.99); p=.042]. The association was stronger among individuals with more recently (<10 years) diagnosed cancer [HR (95% CI) = 0.89 (0.81, 0.98); p=.019]. Conclusion: In a cohort of cardio-oncologic patients, greenness was independently associated with lower mortality. (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.)
Databáze:	MEDLINE
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