The Fate of a Polygenic Phenotype Within the Genomic Landscapes of Introgression in the European Seabass Hybrid Zone.

Autor:	Leitwein M; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France., Durif G; IMAG-Institut Montpelliérain Alexander Grothendieck, 34000 Montpellier, France., Delpuech E; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France., Gagnaire PA; ISEM, Univ Montpellier, CNRS, EPHE, IRD, 34000 Montpellier, France., Ernande B; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France., Vandeputte M; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France., Vergnet A; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France., Duranton M; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France., Clota F; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France., Allal F; UMR Marbec, Université Montpellier, CNRS, Ifremer, IRD, INRAE, 34000 Montpellier, France.
Jazyk:	angličtina
Zdroj:	Molecular biology and evolution [Mol Biol Evol] 2024 Sep 04; Vol. 41 (9).
DOI:	10.1093/molbev/msae194
Abstrakt:	Unraveling the evolutionary mechanisms and consequences of hybridization is a major concern in biology. Many studies have documented the interplay between recombination and selection in modulating the genomic landscape of introgression, but few have considered how associations with phenotype may affect this landscape. Here, we use the European seabass (Dicentrarchus labrax), a key species in marine aquaculture that undergoes natural hybridization, to determine how selection on phenotype modulates the introgression landscape between Atlantic and Mediterranean lineages. We use a high-density single nucleotide polymorphism array to assess individual local ancestry along the genome and improve the mapping of muscle fat content, a polygenic trait that is divergent between lineages. Taking into account variation in recombination rates, we reveal a purging of Atlantic ancestry in the admixed Mediterranean populations. While Atlantic individuals had higher muscle fat content, we observed that genomic regions associated with this trait in Mediterranean populations displayed reduced introgression of Atlantic ancestry. These results emphasize how selection against maladapted alleles shapes the genomic landscape of introgression. Competing Interests: Conflict of Interest The authors declare that there is no conflict of interest. (© The Author(s) 2024. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution.)
Databáze:	MEDLINE
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