| Autor: |
Li XY; Core Facility of Wuhan University, Wuhan University, Wuhan 430072, PR China., Zhou XD; Core Facility of Wuhan University, Wuhan University, Wuhan 430072, PR China., Hu JM; Core Facility of Wuhan University, Wuhan University, Wuhan 430072, PR China. |
| Jazyk: |
angličtina |
| Zdroj: |
Analytical methods : advancing methods and applications [Anal Methods] 2024 Oct 10; Vol. 16 (39), pp. 6589-6598. Date of Electronic Publication: 2024 Oct 10. |
| DOI: |
10.1039/d4ay01232a |
| Abstrakt: |
By means of their specific interactions with different metal ions, naturally occurring proteins control structures and functions of many biological processes and functions in organisms. In view of natural metallopeptides, scientists have proposed artificial peptides which coordinate with metal ions through their functional groups either for introducing a special reactivity or for constructing various sensors. However, the design of new peptide ligands requires a deep understanding of the structures, assembly properties, and dynamic behaviors of such peptides. This review briefly describes detection strategies of metal ions via coordination to the binding sites in peptides. The principles and functions of sensing systems are described as well. We also highlight some examples of a metal-induced peptide self-assembly with relevance to biotechnology applications. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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