Zeolite-based nanoparticles drug delivery systems in modern pharmaceutical research and environmental remediation.

Autor:	Pandya T; L. J. Institute of Pharmacy, L J University, Ahmedabad, Sanand, Sarkhej-Gandhinagar Highway, 382 210, Gujarat, India., Patel S; Parul Institute of Pharmacy, Parul University, Lambda, Vadodara, 391760, India., Kulkarni M; L. J. Institute of Pharmacy, L J University, Ahmedabad, Sanand, Sarkhej-Gandhinagar Highway, 382 210, Gujarat, India.; Gandhinagar Institute of Pharmacy, Gandhinagar University, Khatraj-Kalol Road, Moti Bhoyan, Kalol, Gandhinagar, 382721, Gujarat, India., Singh YR; L. J. Institute of Pharmacy, L J University, Ahmedabad, Sanand, Sarkhej-Gandhinagar Highway, 382 210, Gujarat, India., Khodakiya A; C.U. Shah College of Pharmacy and Research, C.U. Shah University, Surendranagar-Ahmedabad State Highway, 363030, Gujarat, India., Bhattacharya S; Department of Pharmaceutics, School of Pharmacy & Technology Management, SVKM'S NMIMS Deemed-to-be University, Shirpur, Maharashtra, 425405, India., Prajapati BG; Shree S.K. Patel College of Pharmaceutical Education & Research, Ganpat University, Gujarat, India.; Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand.
Jazyk:	angličtina
Zdroj:	Heliyon [Heliyon] 2024 Aug 16; Vol. 10 (16), pp. e36417. Date of Electronic Publication: 2024 Aug 16 (Print Publication: 2024).
DOI:	10.1016/j.heliyon.2024.e36417
Abstrakt:	This review explores the potential of zeolite-based nanoparticles in modern pharmaceutical research, focusing on their role in advanced drug delivery systems. Zeolites, integrated into polymeric materials, offer precise drug delivery capabilities due to their unique structural features, biocompatibility, and controllable properties. Additionally, zeolites demonstrate environmental remediation potential through ion exchange processes. Synthetic zeolites, with modified release mechanisms, possess distinctive optical and electronic properties, expanding their applications in various fields. The study details zeolites' significance across industrial and scientific domains, outlining synthesis methods and size control techniques. The review emphasizes successful encapsulation and functionalization strategies for drug delivery, highlighting their role in enhancing drug stability and enabling targeted delivery. Advanced characterization techniques contribute to a comprehensive understanding of zeolite-based drug delivery systems. Addressing potential carcinogenicity, the review discusses environmental impact and risk assessment, stressing the importance of safety considerations in nanoparticle research. In biomedical applications, zeolites play vital roles in antidiarrheal, antitumor, antibacterial, and MRI contrast agents. Clinical trials featuring zeolite-based interventions underscore zeolite's potential in addressing diverse medical challenges. In conclusion, zeolite-based nanoparticles emerge as promising tools for targeted drug delivery, showcasing diverse applications and therapeutic potentials. Despite challenges, their unique advantages position zeolites at the forefront of innovative drug delivery systems. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2024 The Authors.)
Databáze:	MEDLINE
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