Preoperative Geriatric Characteristics Associated with Changes in Postoperative Cognitive Function and Quality of Life: a Prospective, Observational Analytic Multicenter Study.

Autor:	Isngadi I; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Brawijaya University/ Dr. Saiful Anwar General Hospital, Malang, Indonesia., Asmoro AA; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Brawijaya University/ Dr. Saiful Anwar General Hospital, Malang, Indonesia., Huda N; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Brawijaya University/ Dr. Saiful Anwar General Hospital, Malang, Indonesia., Siswagama TA; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Brawijaya University/ Dr. Saiful Anwar General Hospital, Malang, Indonesia., Rehatta NM; Anesthesiology and Reanimation Department, Faculty of Medicine, Airlangga University/ Dr. Soetomo General Hospital, Surabaya, Indonesia., Chandra S; Anesthesiology and Intensive Care Department, Faculty of Medicine, University of Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia., Sari D; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Public Health, and Nursing, Gadjah Mada University/ Dr. Sardjito General Hospital, Yogyakarta, Indonesia., Lestari MI; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Sriwijaya University/ Dr. Mohammed Hoesin General Hospital, Palembang, Indonesia., Senapathi TG; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Udayana University/ Sanglah General Hospital, Denpasar, Indonesia., Nurdin H; Anesthesiology and Intensive Care Department, Faculty of Medicine, Hasanuddin University/ Dr. Wahidin Sudirohusodo General Hospital, Makassar, Indonesia., Wirabuana B; Anesthesiology and Reanimation Department, Faculty of Medicine, Airlangga University/ Dr. Soetomo General Hospital, Surabaya, Indonesia., Pramodana B; Anesthesiology and Intensive Care Department, Faculty of Medicine, University of Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia., Pradhana AP; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Udayana University/ Sanglah General Hospital, Denpasar, Indonesia., Anggraeni N; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Riau University/ Arifin Achmad General Hospital, Riau, Indonesia., Sikumbang KM; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Riau University/ Arifin Achmad General Hospital, Riau, Indonesia., Halimi RA; Anesthesiology and Intensive Care Department, Faculty of Medicine, Lambung Mangkurat University/ Ulin General Hospital, Banjarmasin, Indonesia., Jasa ZK; Anesthesiology and Intensive Care Department, Faculty of Medicine, Padjadjaran University/ Dr. Hasan Sadikin General Hospital, Bandung, Indonesia., Nasution AH; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Universitas Sumatera Utara/ Dr. Adam Malik General Hospital, Medan, Indonesia., Mochamat M; Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Diponegoro University/ Dr. Kariadi General Hospital, Semarang, Indonesia., Purwoko P; Anesthesiology and Intensive Care, Sebelas Maret University Faculty of Medicine, Surakarta, Indonesia.
Jazyk:	angličtina
Zdroj:	Annals of geriatric medicine and research [Ann Geriatr Med Res] 2024 Sep 12. Date of Electronic Publication: 2024 Sep 12.
DOI:	10.4235/agmr.24.0102
Abstrakt:	Background: Changes in cognitive function are associated with increased depression and decreased quality of life (QOL). This study aimed to determine the relationship between the characteristics of geriatric patients and anesthetic management with changes in postoperative cognitive function and QOL of geriatric patients undergoing elective surgery. Methods: This prospective observational analytic multicenter study included patients aged ≥60 years who underwent elective surgery in hospitals in Indonesia. We used the whole sampling method and performed follow-up 30 days after surgery. Data were analyzed using bivariate chi-square and multivariate regression tests with a confidence interval of 95% and α=5%. Results: Among the 933 geriatric patients included in this study (55.0% female), most (59.8%) received general anesthesia. Factors including age (p<0.001, B=-0.374, odds ratio [OR]=0.688), body mass index (BMI) (p<0.05, B=0.129, OR=1.138), and physical status based on American Society of Anesthesiologists (ASA) classification (p<.001, B=-0.458, OR=0.633) were significantly associated with postoperative cognitive function. BMI (p<.001, B=-0.218, OR=1.244), absence of comorbidities (p<0.05, B=-0.312, OR=0.732), regional anesthesia (p<0.05, B=0.606, OR=1.883), and changes in cognitive function (p<0.05, B=0.288, OR=1.334) were significantly correlated with changes in postoperative QOL. Conclusion: Age, BMI, and ASA physical status were significantly associated with postoperative cognitive function in geriatric patients, whereas BMI, comorbidities, regional anesthesia, and changes in postoperative cognitive function were associated with QOL. These preoperative factors can predict postoperative cognitive function and QOL and may be useful during preoperative planning.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu