Utilizing sulfa drugs' pH-dependent spectral modifications for designing molecular logic gates.

Autor: Vibha K; Department of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583 105, India., Prachalith NC; Department of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583 105, India., Kumar HMS; Department of Physics, Siddaganga Institute of Technology, Tumakuru, Karnataka 572103, India., Ravikantha MN; Department of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583 105, India; Department of Physics, Government Science College, Chitradurga 577 501, India., Reddy RA; Department of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583 105, India; Department of Physics, GVVP GFGC, Hagari Bommanahalli 583 212, India., Thipperudrappa J; Department of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583 105, India. Electronic address: jtrphy2007@gmail.com.
Jazyk: angličtina
Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2025 Jan 15; Vol. 325, pp. 125099. Date of Electronic Publication: 2024 Sep 06.
DOI: 10.1016/j.saa.2024.125099
Abstrakt: In this study, the absorption and fluorescence characteristics of sulfa drugs, specifically Sulfadiazine (SDZ), Sulfamerazine (SMZ), and Sulfamethazine (STZ), were examined across a pH range of 1-14. The absorption and fluorescence spectra of these sulfa drugs showed significant changes depending on the pH value. Analysis of their pH-dependent absorption and fluorescence properties indicated that these sulfa drugs could used to design molecular logic gates. The absorption and fluorescence behaviors at various wavelength maxima were utilized to design IMPLICATION and Improved-INHIBIT (I-INHIBIT) molecular logic gates.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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