Mechanisms underlying the development of type 1 diabetes in ART-treated people living with HIV: an enigmatic puzzle.

Autor: Zaongo SD; Department of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China., Zongo AW; College of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China., Chen Y; Department of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.
Jazyk: angličtina
Zdroj: Frontiers in immunology [Front Immunol] 2024 Aug 27; Vol. 15, pp. 1470308. Date of Electronic Publication: 2024 Aug 27 (Print Publication: 2024).
DOI: 10.3389/fimmu.2024.1470308
Abstrakt: The immunopathogenesis of HIV infection remains poorly understood. Despite the widespread use of effective modern antiretroviral therapy (ART), people living with HIV (PLWH) are known to develop several comorbidities, including type 1 diabetes (T1DM). However, the etiology and critical mechanisms accounting for the onset of T1DM in the preceding context remain unknown. This article proposes to address this topic in order to provide further understanding and future research directions.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2024 Zaongo, Zongo and Chen.)
Databáze: MEDLINE