Telomere dynamics as mediators of gut microbiota-host interactions.

Autor: Pepke ML; Center for Evolutionary Hologenomics, Globe Institute, Faculty of Health and Medical Sciences, Øster Farimagsgade 5, DK-1353 Copenhagen, University of Copenhagen, Denmark. Electronic address: michael@pepke.dk., Hansen SB; Center for Evolutionary Hologenomics, Globe Institute, Faculty of Health and Medical Sciences, Øster Farimagsgade 5, DK-1353 Copenhagen, University of Copenhagen, Denmark., Limborg MT; Center for Evolutionary Hologenomics, Globe Institute, Faculty of Health and Medical Sciences, Øster Farimagsgade 5, DK-1353 Copenhagen, University of Copenhagen, Denmark.
Jazyk: angličtina
Zdroj: Trends in cell biology [Trends Cell Biol] 2024 Oct; Vol. 34 (10), pp. 805-808. Date of Electronic Publication: 2024 Sep 09.
DOI: 10.1016/j.tcb.2024.08.003
Abstrakt: The highly proliferative gut tissue exhibits rapid telomere shortening with systemic effects on the host organism. Recent studies have demonstrated a bidirectionality in interactions between intestinal telomere length dynamics and the composition and activity of the gut microbiome thus linking processes of inflammation, dysbiosis and aging across different vertebrate species.
Competing Interests: Declaration of interests The authors declare no competing interests.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: