The effect of Momordica charantia extract on sheep infected with Haemonchus contortus.

Autor: Alves AMJT; Department of Agricultural Science of the State University of Montes Claros (UNIMONTES), 39448-524 Janaúba, MG, Brazil., Oliveira LLDS; Department of Agricultural Science of the State University of Montes Claros (UNIMONTES), 39448-524 Janaúba, MG, Brazil. Electronic address: laura.oliveira@unimontes.br., Silva GLS; Department of Agricultural Science of the State University of Montes Claros (UNIMONTES), 39448-524 Janaúba, MG, Brazil., Dornelas MEO; Department of Agricultural Science of the State University of Montes Claros (UNIMONTES), 39448-524 Janaúba, MG, Brazil., D'Angelo MFSV; Department of Computer Science at the State University of Montes Claros (UNIMONTES), 39401-089 Montes Claros, MG, Brazil. Electronic address: marcos.dangelo@unimontes.br., Oliveira DF; Department of Chemistry Federal University of Lavras, 37203-202 Lavras, MG, Brazil. Electronic address: denilson@ufla.br., Lima WDS; Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), 31270-901 Belo Horizonte, MG, Brazil. Electronic address: wlima@icb.ufmg.br., Pereira CAJ; Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), 31270-901 Belo Horizonte, MG, Brazil., Silva FVE; Department of Agricultural Science of the State University of Montes Claros (UNIMONTES), 39448-524 Janaúba, MG, Brazil. Electronic address: fredson.silva@unimontes.br.
Jazyk: angličtina
Zdroj: Research in veterinary science [Res Vet Sci] 2024 Nov; Vol. 180, pp. 105401. Date of Electronic Publication: 2024 Sep 04.
DOI: 10.1016/j.rvsc.2024.105401
Abstrakt: Bitter melon (Momordica charantia) has several biological properties including anthelmintic activity. Presented in vivo study evaluated the anthelmintic activity of the hydroalcoholic extract of M. charantia Presented in vivo study (HEMC) and its effect on animal performance, carcass characteristics and lamb meat quality in animals infected by Haemonchus contortus. The HEMC demonstrated effectiveness against the parasite. Lambs treated with HEMC showed a significant reduction in egg count per gram of faeces and in the number of parasites in the abomasum. However, nutrient intake decreased with increasing doses of HEMC, leading to reductions in final live weight and carcass weight. No significant effects were observed on meat quality. Therefore, it is concluded that HEMC presents anthelmintic action, but it also impairs animal performance, highlighting the need to assess the benefits and impacts of HEMC use for H. contortus control.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Laura reports administrative support and equipment, drugs, or supplies were provided by National Council for Scientific and Technological Development.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: