Incidence, outcomes, and predictors of new heart failure in syrian conflict-affected population following hospitalization for atrial fibrillation: A retrospective cohort study.

Autor:	Antoun I; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; Faculty of Medicine, University of Aleppo, Aleppo, Syria., Alkhayer A; University of Tishreen's Hospital, Latakia, Syria., Aljabal M; Leicestershire Partnership NHS Trust, Leicester, UK., Mahfoud Y; University of Tishreen's Hospital, Latakia, Syria., Alkhayer A; University of Tishreen's Hospital, Latakia, Syria., Kotb AI; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Barker J; National Heart and Lung Institute, Imperial College London, London, UK., Somani R; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; Department of Cardiac Surgery, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK., Ng GA; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK.; Department of Cardiology, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK., Zakkar M; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; Department of Cardiac Surgery, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.; Faculty of Medicine, University of Damascus, Damascus, Syria.
Jazyk:	angličtina
Zdroj:	Perfusion [Perfusion] 2024 Sep 10, pp. 2676591241283883. Date of Electronic Publication: 2024 Sep 10.
DOI:	10.1177/02676591241283883
Abstrakt:	Background: Atrial fibrillation (AF) is the most common arrhythmia worldwide. Data regarding readmission for new congestive heart failure (CHF) following index admission for AF in the developing world are poorly described. Objectives: The study aimed to assess the rate, predictors, and outcomes of 120-day CHF readmission after index admission for AF in Syria. Methods: This retrospective cohort study collected all adult patients without known CHF who had an index admission with AF to Latakia's tertiary center between June 2021-December 2023. Data were taken from patients' medical notes. The primary outcome included readmission with incident CHF within 120 of index discharge, and secondary outcomes included predictors and outcomes of these CHF readmissions. Results: A total of 660 patients were included in the final analysis, of which 69 (11.7%) were readmitted with new CHF within 120 days of index discharge. Readmitted patients had higher median age (58 vs 70 years, p < .001). Factors that independently increased 120-day CHF incidence were age ≥60 years (HR: 9.8, 95% CI: 4.8-23.6, p < .001), diabetes mellitus (DM) (HR:2.9, 95% CI:1.7-4.9, p < .001), valvular heart disease (VHD) (HR:1.7, 95% CI:1.04-2.78, p = .047), and hypertension (HR:2.5, 95% CI:1.5-4, p < .001). Inpatient mortality occurred in six readmitted patients (9%). LVEF <40% (HR:6.7, 95% CI: 24.31, p = .01) and DM (HR:7.2, 95% CI: 1.9-33, p = .004) were independently associated with inpatient mortality. Conclusion: Hospitalization for new CHF was common in Syrian patients discharged with AF. The clinical predictors of incident CHF emphasize the importance of integrated management of lifestyle risk factors and common comorbidities in AF patients to optimize outcomes in resource-depleted communities. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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