| Autor: |
Ahmad R; 'New-Senior' Oriented Smart Health Care Education Center, Pukyong National University, Busan 48513, Republic of Korea. ahmadrafiq38@gmail.com., Masrat S; Centre for Nanoscience and Nanotechnology, Jamia Millia Islamia, New Delhi 110025, India. rafia.masrat@gmail.com., Rehman MT; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. malajmii@ksu.edu.sa., AlAjmi MF; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. malajmii@ksu.edu.sa., Alam S; Department of Pharmacology & Therapeutics, Roswell Park Cancer Institute, Buffalo, New York 14263, USA. shamshad.alam@roswellpark.org., Mishra P; Quantum Materials and Devices Laboratory, Faculty of Engineering and Technology, Jamia Millia Islamia (Central University), New Delhi 110025, India. pmishra@jmi.ac.in., Lee BI; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea. bilee@pknu.ac.kr.; Digital Healthcare Research Center, Institute of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of Korea.; Division of Smart Healthcare, College of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of Korea. |
| Abstrakt: |
Utilizing nanomaterials on the working electrode of sensors enables the fabrication of highly sensitive devices for the detection of various analytes. Herein, a facile synthesis method is used to formulate a grain-like cerium oxide (CeO 2 ) nanostructure. The structural features and surface properties of the synthesized CeO 2 nanostructure were studied, which showed that the CeO 2 nanostructure exhibited grain-like morphology, good crystalline structure, and excellent vibrational properties. To evaluate the sensing properties of grain-like CeO 2 nanostructure, nanomaterial slurry was prepared in butyldiglycol acetate binder. Then, the nanomaterial slurry was drop-casted onto the working electrode of the screen-printed carbon electrode (SPCE) to fabricate the CeO 2 -modified SPCE sensor. The sensor's electrochemical properties were analysed, which showed excellent charge-transfer behavior compared to the bare SPCE. CV-based electrochemical sensing of uric acid (UA) on a CeO 2 -modified SPCE sensor exhibited excellent linear performance up to 1070 μM UA. Moreover, the sensor offers good sensitivity, low detection limit, reproducibility, selectivity, and long-term stability. The CeO 2 -modified SPCE sensor demonstrated a promising application for UA detection in real samples, addressing the need for timely UA concentration monitoring. |
