Differences in mortality and risk factors, two years after endovascular repair of ruptured abdominal aortic aneurysms - Reassessment analysis.

Autor: Antoń B; Department of General, Vascular, Endocrine and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland., Małyszko J; Department of Nephrology, Dialysis and Internal Medicine, Medical University of Warsaw, Warsaw, Poland., Stabiszewski P; Department of Vascular Surgery, St. Padre Pio Provincial Hospital in Przemyśl, Przemyśl, Poland., Kaszczewski P; Department of General, Vascular, Endocrine and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland., Antoń P; Department of Vascular Surgery, University of Warmia and Mazury, Olsztyn, Poland., Kuźma Ł; Department of Invasive Cardiology, Medical University of Bialystok, Bialystok, Poland., Nazarewski S; Department of General, Vascular, Endocrine and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland., Gałązka Z; Department of General, Vascular, Endocrine and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland.
Jazyk: angličtina
Zdroj: Renal failure [Ren Fail] 2024 Dec; Vol. 46 (2), pp. 2397051. Date of Electronic Publication: 2024 Sep 09.
DOI: 10.1080/0886022X.2024.2397051
Abstrakt: Objective: The prevalence of abdominal aortic aneurysms (AAA) increases with age. Elective intervention for AAA is critical to prevent rupture associated with very high mortality among older males.
Methods: The aim of this study was to address the impact of post-contrast acute kidney-PC-AKI injury among patients treated with endovascular repair of ruptured AAA-EVAR on outcomes such as new onset chronic kidney disease-CKD and mortality among patients within a two-year trial.
Results: The same study group (of n  = 192 patients) underwent reassessment, two years after EVAR treatment. The overall mortality rate was 16.67%, and it was higher in the AKI group - 38.89%. CKD patients had a mortality rate of 23.88% ( n  = 16). Among patients with an aneurysm diameter >67 mm mortality rate reached 20% ( n  = 6), while in the previously reported diabetes mellitus group 37.93% ( n  = 11). New onset of CKD was diagnosed in 23% of cases. Preexisting CKD patients with PC- AKI contributed to a 33.33% mortality rate ( n  = 8).
Conclusion: This study concludes that PC-AKI impacts outcomes and survival in endovascularly treated AAAs. Type 2 diabetes and preexisting chronic kidney disease are associated with higher mortality within a 2-year follow-up, however gender factor was not significant. A larger aneurysm diameter is related with a higher prevalence of PC-AKI. These factors should be taken into account during screening, qualifying patients for the treatment and treating patients with AAA. It may help to identify high-risk individuals and tailor preventive measurements and treatment options accordingly, improving treatment results and reducing mortality.
Databáze: MEDLINE