Clinical Characteristics and Therapeutic Management of Atopic Dermatitis in Elderly Patients Compared with Young Adult Patients: A Prospective Multicentre Study.

Autor:	Pollyn-Millot C; Department of Dermatology, University Hospital of Amiens, Amiens, France., Maccari F; Department of Dermatology, Military Teaching Hospital Bégin, Saint Mandé, France; Dermatology, Private Practice, Saint-Maur-des-Fossés, France., Perrot JL; Department of Dermatology, University Hospital of Saint-Etienne, Saint-Etienne, France., Reguiai Z; Department of Dermatology, Polyclinique Courlancy-Bezannes, Reims, France., Boulard C; Department of Dermatology, Jacques Monod Hospital, Le Havre, France., Becherel PA; Department of Dermatology, Antony Private Hospital, Antony, France., Poreaux C; Department of Dermatology, Stanislas-Nancy Medical Center, Nancy, France., Mery-Bossard L; Department of Dermatology, François Quesnay Hospital, Mantes La Jolie, France., Beaulieu D; Department of Dermatology, Poissy/Saint-Germain-en-Laye Hospital, Saint-Germain-en-Laye, France., Pourchot D; Department of Dermatology, Victor Dupouy Hospital, Argenteuil, France., Fougerousse AC; Department of Dermatology, Military Teaching Hospital Bégin, Saint Mandé, France., Begon E; Department of Dermatology, Pontoise Hospital, Pontoise, France., Liegeon AL; Department of Dermatology, Metz-Thionville Regional Hospital Center, Thionville, France., Fite C; Department of Dermatology, Paris Saint Joseph, Hospital Paris, France., Zaraa I; Department of Dermatology, Paris Saint Joseph, Hospital Paris, France., Lons-Danic D; Department of Dermatology, Paris Saint Joseph, Hospital Paris, France., Walls B; Department of Dermatology, Paris Saint Joseph, Hospital Paris, France., Jacobzone C; Department of Dermatology, Groupe Hospitalier Bretagne Sud-Hôpital du Scorff, Lorient, France., Lepelley C; Dermatology, Private Practice, Vannes, France., Denis D; Dermatology, Private Practice, Vannes, France., Chaby G; Department of Dermatology, University Hospital of Amiens, Amiens, France. chaby.guillaume@chu-amiens.fr.
Jazyk:	angličtina
Zdroj:	Acta dermato-venereologica [Acta Derm Venereol] 2024 Sep 09; Vol. 104, pp. adv40420. Date of Electronic Publication: 2024 Sep 09.
DOI:	10.2340/actadv.v104.40420
Abstrakt:	Atopic dermatitis (AD) is the most common chronic inflammatory dermatitis in developed countries, and has a major impact on those affected. Little is known about AD in elderly patients. This prospective multicentre observational study described the clinical characteristics and burden of AD in elderly subjects ≥ 65 years, as well as the therapeutic options chosen for this population in routine care, and compared findings with those in young adults with AD < 30 years. Cohort data from adult patients with moderate-to-severe AD enrolled in a French national prospective registry (December 2020 to May 2023) were analysed. Patients ≥ 65 years made up 12.5% of the total adult cohort and presented less head-and-neck and extremity involvement, and were less affected by generalized forms than young adult patients. Elderly patients predominantly had late-onset AD and had similar disease severity to younger adults. Although the overall impact of AD appeared to be lower in elderly patients and treatment was initially less used in this age group, the substantial impact on sleep and psychiatric comorbidities was similar in older and younger adult patients. Better understanding of AD in elderly patients and the establishment of age-specific treatment guidelines may help dermatologists manage the disease in older people.
Databáze:	MEDLINE
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