An Inflammatory Myofibroblastic Tumour Presenting with Limited Mouth-Opening, Hypoesthaesia of The Left Chin and Infraorbital Area, Intermittent Left Eye Ptosis and Converging Strabismus.

Autor:	Ben Hassine I; Faculty of Medicine, University of Sousse, Susa, Tunisia.; Internal Medicine Department, Sahloul University Hospital, Susa, Tunisia.; Geriatric medicine and Gerontology Unit, University of Sousse, Susa, Tunisia., Romdhane W; Faculty of Medicine, University of Sousse, Susa, Tunisia.; Internal Medicine Department, Sahloul University Hospital, Susa, Tunisia.; Geriatric medicine and Gerontology Unit, University of Sousse, Susa, Tunisia., Belkacem R; Department of Oral Medicine and Oral Surgery, Sahloul University Hospital, Susa, Tunisia., Anoun J; Faculty of Medicine, University of Sousse, Susa, Tunisia.; Internal Medicine Department, Sahloul University Hospital, Susa, Tunisia.; Geriatric medicine and Gerontology Unit, University of Sousse, Susa, Tunisia., Baya W; Faculty of Medicine, University of Sousse, Susa, Tunisia.; Internal Medicine Department, Sahloul University Hospital, Susa, Tunisia.; Geriatric medicine and Gerontology Unit, University of Sousse, Susa, Tunisia., Mzabi A; Faculty of Medicine, University of Sousse, Susa, Tunisia.; Internal Medicine Department, Sahloul University Hospital, Susa, Tunisia.; Geriatric medicine and Gerontology Unit, University of Sousse, Susa, Tunisia., Ben Fredj F; Faculty of Medicine, University of Sousse, Susa, Tunisia.; Internal Medicine Department, Sahloul University Hospital, Susa, Tunisia.; Geriatric medicine and Gerontology Unit, University of Sousse, Susa, Tunisia.
Jazyk:	angličtina
Zdroj:	European journal of case reports in internal medicine [Eur J Case Rep Intern Med] 2024 Aug 23; Vol. 11 (9), pp. 004568. Date of Electronic Publication: 2024 Aug 23 (Print Publication: 2024).
DOI:	10.12890/2024_004568
Abstrakt:	An inflammatory myofibroblastic tumour (IMT) is a rare neoplasm of mesenchymal origin, defined by myofibroblastic spindle cells accompanied by inflammatory cells, lymphocytes and eosinophils. Its symptomatology depends on the involved site and tends to mimic a malignant tumour clinically and radiologically. The head and neck region accounts for 5% of all IMTs. Here, we report a case of a 35-year-old woman, with no medical history, who presented with a mouth-opening limitation of 8 mm evolving for three years and occurring six months after of a wisdom tooth extraction. She also experienced a recent occurrence of left eye ptosis and a converging strabismus. On examination, the patient had a body temperature at 37°C, with hypoesthaesia of the left chin and infraorbital area, without any other abnormality. Laboratory examinations did not reveal a biological inflammatory syndrome or rhabdomyolysis. The infectious investigations were all negative, as well as the immunological tests, in particular negative for anti-AChR and anti-MuSK antibodies. On the facial computed tomography (CT) scan, we noted an active reshuffle in the left mandible ascending branch with a thickening of the ipsilateral pterygoid muscles and the left temporal meningeal tissue. After corticosteroid therapy 0.7 mg/kg/j, we obtained an improvement in the patient's mouth-opening, thus a biopsy of the lesion was performed under local anaesthesia, revealing IMT. The patient continued the corticosteroids therapy with a progressive tapering resulting in a marked clinical improvement of the mouth-opening limitation and her ptosis. Learning Points: An inflammatory myofibroblastic tumour (IMT) is a challenging disease.Given the variable clinical and radiological presentation of the disease, it is of paramount importance to know it, to be swiftly recognised so diagnosis can be promptly made.The adapted treatment should be immediately started to prevent possible life-threatening outcomes. Competing Interests: Conflicts of Interests: The Authors declare that there are no competing interests. (© EFIM 2024.)
Databáze:	MEDLINE
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