Feasibility and Safety of Early Oral Feeding After Radical Gastrectomy in Patients With Gastric Carcinoma: A Systematic Review.

Autor:	Ali W; General Surgery, Jamhuriat Hospital, Kabul, AFG., Dost W; Medicine and Surgery, Kabul University of Medical Sciences, Kabul, AFG.; General Surgery, Jamhuriat Hospital, Kabul, AFG., Zaman MN; General Surgery, Jamhuriat Hospital, Kabul, AFG., Rasully MQ; General Surgery, Jamhuriat Hospital, Kabul, AFG., Niazi J; Cardiovascular Surgery, Punjab Institute of Cardiology, Lahore, PAK., Qasemi F; General Surgery, Jamhuriat Hospital, Kabul, AFG., Dost R; Cardiac Surgery, Kabul University of Medical Sciences, Kabul, AFG., Dost W; Cardiac Surgery, Kabul University of Medical Sciences, Kabul, AFG., Bakht D; Medicine and Surgery, Mayo Hospital, Lahore, PAK., Bokhari SFH; Surgery, King Edward Medical University, Lahore, PAK.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Aug 08; Vol. 16 (8), pp. e66463. Date of Electronic Publication: 2024 Aug 08 (Print Publication: 2024).
DOI:	10.7759/cureus.66463
Abstrakt:	This systematic review examines the feasibility and safety of early oral feeding (EOF) after radical gastrectomy in patients with gastric cancer. A comprehensive literature search identified eight eligible studies, including both clinical trials and cohort studies, conducted between 2011 and 2020. The review analyzed outcomes such as postoperative complications, length of hospital stay, time to first flatus/bowel movement, and changes in nutritional markers. The findings suggest that EOF is generally feasible and well-tolerated, with high adherence rates reported across studies. Most patients successfully initiated oral intake within 72 hours post-surgery without significant protocol deviations. Regarding safety, the studies reported comparable or lower rates of postoperative complications in EOF groups compared to traditional feeding protocols, though some noted non-significant increases in complications with EOF. Several studies observed potential benefits of EOF, including shorter hospital stays, earlier return of gastrointestinal function, and improved nutritional status. However, the results were mixed, with some studies finding no significant differences in these outcomes. While the review suggests EOF is a viable option for postoperative management after radical gastrectomy, it emphasizes the importance of patient-specific factors and close monitoring during implementation. The heterogeneity in study designs, EOF protocols, and outcome measures limits direct comparisons. Future large-scale randomized controlled trials are warranted to establish standardized EOF protocols and provide more robust evidence for this patient population. Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Ali et al.)
Databáze:	MEDLINE
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