Leukemia in pregnancy: Diagnosis and therapeutic approach (Review).

Autor: Giannakaki AG; First Department of Obstetrics and Gynecology, Alexandra University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece., Giannakaki MN; Department of Internal Medicine, Thriasio General Hospital of Elefsina, 19018 Magoula, Greece., Oikonomou E; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Nikolettos K; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Bothou A; Neonatal Department, Alexandra University Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece., Kotanidou S; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Andreou S; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Kritsotaki N; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Nalmpanti T; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Spanoudakis E; Department of Hematology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Iatrakis G; Department of Obstetrics and Gynecology, Rea Maternity Hospital, National and Kapodistrian University of Athens, 17564 Athens, Greece., Damaskos C; Department of Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.; Renal Transplantation Unit, Laiko General Hospital, 11527 Athens, Greece., Garmpis N; Department of Surgery, Sotiria Hospital, 11527 Athens, Greece., Nikolettos N; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece., Tsikouras P; Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Jazyk: angličtina
Zdroj: Molecular and clinical oncology [Mol Clin Oncol] 2024 Aug 21; Vol. 21 (5), pp. 79. Date of Electronic Publication: 2024 Aug 21 (Print Publication: 2024).
DOI: 10.3892/mco.2024.2777
Abstrakt: The present study aimed to evaluate the epidemiological, diagnostic and therapeutic data of hematological malignancies in pregnancy. Leukemia in pregnancy is rare, and literature data are not extensive. Risk factors, epidemiology and pathogenesis of these diseases are not fully developed. Furthermore, there is a detailed report on the complications in pregnancy and the overall (per trimester) management of these diseases, specifically their treatment strategy. The possibility of achieving a future pregnancy in women with leukemia is described in the present study. The limited clinical research data currently available is mainly due to the inability to conduct randomized clinical trials for ethical reasons. Further research is needed, firstly due to the importance of these diseases for the pregnant woman and the fetus, and secondly, due to the continuous development of novel anticancer drugs that aim to improve the prognosis of these diseases.
Competing Interests: The authors declare that they have no competing interests.
(Copyright: © 2024 Giannakaki et al.)
Databáze: MEDLINE
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