In Vivo Anthelmintic Efficacy of Adansonia digitata and Anogeissus leiocarpa against Haemonchus contortus Infestation Induced in Sheep.

Autor: Kuiseu J; Zootechnics and Livestock Systems Research Unit (URZoSE) National University of Agriculture (UNA), Kétou, Benin.; Laboratory of Toxicology and Environmental Health (LATSE) University of Abomey-Calavi (UAC), Abomey-Calavi, Benin., Konmy B; Zootechnics and Livestock Systems Research Unit (URZoSE) National University of Agriculture (UNA), Kétou, Benin.; Laboratory of Ethnopharmacology and Animal Health (LESA) University of Abomey-Calavi (UAC), Abomey-Calavi, Benin., Dansou CC; Zootechnics and Livestock Systems Research Unit (URZoSE) National University of Agriculture (UNA), Kétou, Benin., Sounkere TTBA; Zootechnics and Livestock Systems Research Unit (URZoSE) National University of Agriculture (UNA), Kétou, Benin., Houssoukpe CG; Zootechnics and Livestock Systems Research Unit (URZoSE) National University of Agriculture (UNA), Kétou, Benin., Hounzangbe-Adote SM; Laboratory of Ethnopharmacology and Animal Health (LESA) University of Abomey-Calavi (UAC), Abomey-Calavi, Benin., Edorh PA; Laboratory of Toxicology and Environmental Health (LATSE) University of Abomey-Calavi (UAC), Abomey-Calavi, Benin., Olounlade PA; Zootechnics and Livestock Systems Research Unit (URZoSE) National University of Agriculture (UNA), Kétou, Benin.; Laboratory of Ethnopharmacology and Animal Health (LESA) University of Abomey-Calavi (UAC), Abomey-Calavi, Benin.
Jazyk: angličtina
Zdroj: Advances in pharmacological and pharmaceutical sciences [Adv Pharmacol Pharm Sci] 2024 Aug 30; Vol. 2024, pp. 3249640. Date of Electronic Publication: 2024 Aug 30 (Print Publication: 2024).
DOI: 10.1155/2024/3249640
Abstrakt: The aim of the present study was to assay the in vivo anthelminthic activity of Anogeissus leiocarpa (Al) family of the Asteraceae and Adansonia digitata (Ad) family of Malvaceae leaf powder against the nematode Haemonchus contortus (Hc) in sheep. Twenty-eight sheep were artificially infected with 3000 Infective larvae (L3) of Hc and divided into four groups. Groups 1 and 2 received 3.2 g/kg of Ad and Al leaf powder according to the body weight for three days by oral route. This treatment was repeated after 14 days. Group 3 received albendazol 5 mg/kg and group 4 received water. The treatment was repeated 14 days later. Examination of faecal samples, packed cell volume and biochemical analyses and necropsy were carried out to determine egg counts, worm burdens, and reduction in worm fecundity and changes in blood parameters. The results showed a reduction in egg excretion of 72.22% and 88.49%, respectively, with Al and Ad leaf powder. Egg laying of adult female worms was reduced by 55.22% and 64.96% with Ad and Al, respectively. FAMACHA score (≤2 in the treated animals) and packed cell volume were improved with Ad and Al. The results of this study revealed that Ad and Al powder may be used as an alternative anthelminthic to control haemonchosis in small ruminants.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2024 Julienne Kuiseu et al.)
Databáze: MEDLINE
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