Maximal respiratory pressure after COVID-19 compared with reference material in healthy adults: A prospective cohort study (The SECURe study).

Autor: Helt TW; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Christensen J; Department of Occupational Therapy and Physiotherapy, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Berg RMG; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Physical Activity Research, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Lund TK; Department of Cardiology, Section for Lung Transplantation, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Kalhauge A; Department of Radiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Rönsholt F; Department of Cardiology, Section for Lung Transplantation, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Podlekareva D; Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Arndal E; Department of Otorhinolaryngology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Madsen F; Center for Clinical Research and Prevention, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark., Munkholm M; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Hanel B; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Lebech AM; Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Katzenstein TL; Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Mortensen J; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jazyk: angličtina
Zdroj: Physiological reports [Physiol Rep] 2024 Sep; Vol. 12 (17), pp. e16184.
DOI: 10.14814/phy2.16184
Abstrakt: After COVID-19 long term respiratory symptoms and reduced lung function including maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) have been reported. However, no studies have looked at MIP and MEP in all disease groups and the reference materials collection methods differ substantially. We aimed to determine MIP and MEP in individuals after COVID-19 infection with different disease severity using reference material of healthy control group obtained using the same standardized method. Patients with COVID-19 were included March 2020-March 2021 at Rigshospitalet, Denmark. MIP and MEP were measured using microRPM. Predicted MIP and MEP were calculated using reference material obtained from 298 healthy adults aged 18-97 years using the same method. In SECURe, 145 participants were measured median 5 months after COVID-19 diagnosis and of these 16% had reduced MIP and/or MEP. There was reduced spirometry and total lung capacity, but not reduced diffusion capacity in those with abnormal MIP and/or MEP compared with normal MIP and MEP. Of those with reduced MIP and/or MEP at 5 months, 80% still had reduced MIP and/or MEP at 12 months follow-up. In conclusion, few have reduced MIP and/or MEP 5 months after COVID-19 and little improvement was seen over time.
(© 2024 The Author(s). Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.)
Databáze: MEDLINE
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