Assessing the effectiveness of greater occipital nerve block in chronic migraine: a systematic review and meta-analysis.

Autor: Mustafa MS; Department of Medicine, Jinnah Sindh Medical University, Karachi, 75510, Pakistan.; Jinnah Sindh Medical University, Rafiqi H J Shaheed Road, Karachi, 75510, Pakistan., Bin Amin S; Department of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, 75400, Pakistan.; Shaheed Mohtarma Benazir Bhutto Medical College, Lyari Hospital Rd, Rangiwara Karachi, Karachi, 75400, Pakistan., Kumar A; Department of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, 75400, Pakistan.; Shaheed Mohtarma Benazir Bhutto Medical College, Lyari Hospital Rd, Rangiwara Karachi, Karachi, 75400, Pakistan., Shafique MA; Department of Medicine, Jinnah Sindh Medical University, Karachi, 75510, Pakistan.; Jinnah Sindh Medical University, Rafiqi H J Shaheed Road, Karachi, 75510, Pakistan., Fatima Zaidi SM; Department of Medicine, Dow University of Health Science, Karachi, 74200, Pakistan.; Dow University of Health Sciences, Mission Rd, New Labour Colony Nanakwara, Karachi, 74200, Pakistan., Arsal SA; Department of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, 75400, Pakistan.; Shaheed Mohtarma Benazir Bhutto Medical College, Lyari Hospital Rd, Rangiwara Karachi, Karachi, 75400, Pakistan., Rangwala BS; Department of Medicine, Jinnah Sindh Medical University, Karachi, 75510, Pakistan.; Jinnah Sindh Medical University, Rafiqi H J Shaheed Road, Karachi, 75510, Pakistan., Iqbal MF; Department of Medicine, Dow University of Health Science, Karachi, 74200, Pakistan.; Dow University of Health Sciences, Mission Rd, New Labour Colony Nanakwara, Karachi, 74200, Pakistan., Raja A; Department of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, 75400, Pakistan.; Shaheed Mohtarma Benazir Bhutto Medical College, Lyari Hospital Rd, Rangiwara Karachi, Karachi, 75400, Pakistan., Haseeb A; Department of Medicine, Jinnah Sindh Medical University, Karachi, 75510, Pakistan.; Jinnah Sindh Medical University, Rafiqi H J Shaheed Road, Karachi, 75510, Pakistan., Jawed I; Department of Medicine, Dow University of Health Science, Karachi, 74200, Pakistan.; Dow University of Health Sciences, Mission Rd, New Labour Colony Nanakwara, Karachi, 74200, Pakistan., Hussien Mohamed Ahmed KA; Faculty of Medicine, University of Khartoum, Khartoum, 11111, Sudan. khabab9722@gmail.com., Muhammad Sinaan Ali S; Department of Medicine, Liaquat National Hospital and Medical College, Karachi, Pakistan.; Liaquat National Hospital & Medical College, Stadium Road, Karachi, 74800, Pakistan., Varrassi G; Fondazione Paolo Procacci, Roma, 00193, Italy.
Jazyk: angličtina
Zdroj: BMC neurology [BMC Neurol] 2024 Sep 07; Vol. 24 (1), pp. 330. Date of Electronic Publication: 2024 Sep 07.
DOI: 10.1186/s12883-024-03834-6
Abstrakt: Background & Aims: Chronic migraine poses a global health burden, particularly affecting young women, and has substantial societal implications. This study aimed to assess the efficacy of Greater Occipital Nerve Block (GONB) in individuals with chronic migraine, focusing on the impact of local anesthetics compared with placebo.
Methods: A meta-analysis and systematic review were conducted following the PRISMA principles and Cochrane Collaboration methods. Eligible studies included case-control, cohort, and randomized control trials in adults with chronic migraine, adhering to the International Classification of Headache Disorders, third edition (ICHD3). Primary efficacy outcomes included headache frequency, duration, and intensity along with safety assessments.
Results: Literature searches across multiple databases yielded eight studies for qualitative analysis, with five included in the final quantitative analysis. A remarkable reduction in headache intensity and frequency during the first and second months of treatment with GONB using local anesthetics compared to placebo has been reported. The incidence of adverse events did not differ significantly between the intervention and placebo groups.
Conclusion: The analysis emphasized the safety and efficacy of GONB, albeit with a cautious interpretation due to the limited number of studies and relatively small sample size. This study advocates for further research exploring various drugs, frequencies, and treatment plans to enhance the robustness and applicability of GONB for chronic migraine management.
(© 2024. The Author(s).)
Databáze: MEDLINE
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