Hantavirus: Preliminary assessment of lateral flow immune assay prototypes to detect IgM and IgG antibodies.

Autor: Guimarães JPT; Institute of Tropical Pathology and Public Health /Universidade Federal de Goiás, Goiânia, GO, Brazil., Fogaça MBT; Institute of Tropical Pathology and Public Health /Universidade Federal de Goiás, Goiânia, GO, Brazil., Moura RS; Centro Universitário Unievangélica, Anápolis, GO, Brazil., Mendonça M; Universidade Federal do Agreste de Pernambuco, Garanhuns, PE, Brazil; Technology Development Center, Biotechnology Nucleus/Universidade Federal de Pelotas, Pelotas, RS, Brazil., Conceição FR; Technology Development Center, Biotechnology Nucleus/Universidade Federal de Pelotas, Pelotas, RS, Brazil., Gimaque JBL; Tropical Medicine Foundation Heitor Vieira Dourado, Manaus, AM, Brazil., de Almeida THP; Tropical Medicine Foundation Heitor Vieira Dourado, Manaus, AM, Brazil., Abrain C; Hospital Foundation of Hematology and Hemotherapy of Amazon, Manaus, AM, Brazil., Mourão MPG; Tropical Medicine Foundation Heitor Vieira Dourado, Manaus, AM, Brazil; Universidade do Estado do Amazonas, Manaus, AM, Brazil., Figueiredo LTM; Virology Research Center /São Paulo University/Ribeirão Preto Unity, SP, Brazil., Stefani MMA; Institute of Tropical Pathology and Public Health /Universidade Federal de Goiás, Goiânia, GO, Brazil., Bührer-Sékula S; Institute of Tropical Pathology and Public Health /Universidade Federal de Goiás, Goiânia, GO, Brazil. Electronic address: samira@buhrer.net.
Jazyk: angličtina
Zdroj: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2024 Dec; Vol. 110 (4), pp. 116521. Date of Electronic Publication: 2024 Sep 02.
DOI: 10.1016/j.diagmicrobio.2024.116521
Abstrakt: Three lateral flow immunoassay prototypes developed to detect IgM, IgG and IgM/IgG antibodies against Hantavirus were evaluated. A total of 163 samples were tested: 10 from Hantavirus patients, 103 from related diseases, and 50 from healthy controls. The prototypes exhibited 100 % sensitivity, 97.5 % to 99.3 % specificity, indicating promising improved diagnosis.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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