The Tiny Big Difference: Nanotechnology in Photoprotective Innovations - A Systematic Review.

Autor: Nascimento Júnior JAC; Postgraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Brazil. adaocarvalho@academico.ufs.br., Santos AM; Postgraduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Brazil., Oliveira AMS; Postgraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Brazil., Santos AB; Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Brazil., de Souza Araújo AA; Postgraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Brazil.; Postgraduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Brazil.; Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Brazil., Aragón DM; Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional da Colombia, Bogotá, D.C, Colombia., Frank LA; Postgraduate Program in Pharmaceutical Sciences, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil.; Núcleo de Terapias Nanotecnológicas (NTnano), Federal University of Rio Grande Do Sul, Porto Alegre, Brazil., Serafini MR; Postgraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Brazil. mairim@academico.ufs.br.; Postgraduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Brazil. mairim@academico.ufs.br.; Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Brazil. mairim@academico.ufs.br.
Jazyk: angličtina
Zdroj: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Sep 07; Vol. 25 (7), pp. 212. Date of Electronic Publication: 2024 Sep 07.
DOI: 10.1208/s12249-024-02925-4
Abstrakt: UV radiation causes long- and short-term skin damage, such as erythema and skin cancer. Therefore, the use of sunscreens is extremely important. However, concerns about UV filter safety have prompted exploration into alternative solutions, with nanotechnology emerging as a promising avenue. This systematic review identified 23 experimental studies utilizing nanocarriers to encapsulate sunscreens with the aim of enhancing their efficacy and safety. Polymeric and lipid nanoparticles are frequently employed to encapsulate both organic and inorganic UV filters along with natural antioxidants. Nanocarriers have demonstrated benefits including reduced active ingredient usage, increased sun protection factor, and mitigated photoinstability. Notably, they also decreased the skin absorption of UV filters. In summary, nanocarriers represent a viable strategy for improving sunscreen formulations, offering enhanced physicochemical properties and bolstered photoprotective effects, thereby addressing concerns regarding UV filter safety and efficacy in cosmetic applications.
(© 2024. The Author(s), under exclusive licence to American Association of Pharmaceutical Scientists.)
Databáze: MEDLINE
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