Psychosis Risk: Time to Look Empirically at a First-step Economical-pragmatic Way to Examine Anomalous Self-experience. Exploring the SQuEASE-11.

Autor: Møller P; Department of Mental Health Research and Development, Division of Mental Health and Addiction, Vestre Viken Hospital Trust, Drammen, Norway., Nelson B; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., McGorry PD; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Mei C; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Amminger GP; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Yuen HP; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Kerr M; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Spark J; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Wallis N; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Polari A; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia.; Orygen Specialist Program, Melbourne, Victoria, Australia., Baird S; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Buccilli K; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Dempsey SA; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Ferguson N; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Formica M; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Krcmar M; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Quinn AL; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Mebrahtu Y; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Ruslins A; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Street R; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia., Dixon L; Department of Psychiatry, Columbia University, New York, NY., Carter C; Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA., Loewy R; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA., Niendam TA; Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA., Shumway M; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA., Wannan C; Orygen, Melbourne, Victoria, Australia.; Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia.
Jazyk: angličtina
Zdroj: Schizophrenia bulletin [Schizophr Bull] 2024 Sep 06. Date of Electronic Publication: 2024 Sep 06.
DOI: 10.1093/schbul/sbae149
Abstrakt: Background: Since the late 1990s, there has been a worldwide surge of scientific interest in the pre-psychotic phase, resulting in the introduction of several clinical tools for early detection. The predictive accuracy of these tools has been limited, motivating the need for methodological and perspectival improvements. The EASE manual supports systematic assessment of anomalous self-experience, and proposes an overall model of understanding how most psychotic experiences may be initially generated on the basis of a unifying, fundamental, pre-reflective distortion of subjectivity.
Study Design: The EASE is time-consuming, so in order to spread the use of this essential perspective of psychosis risk we selected prototypical and frequent phenomena from the EASE, combining them into SQuEASE-11. To investigate this instrument for clinical relevance, basic psychometric properties, factor structure, and relationships with gold standard instruments and the full EASE, it was administered as an interview in the STEP intervention trial (Melbourne, Australia), with 328 clinical high-risk for psychosis (CHR-P) patients.
Study Results: The SQuEASE-11 had moderate internal consistency and revealed two correlated factors. Significant relationships were observed between the SQuEASE-11 and the widely used and validated instruments CAARMS, BPRS, SANS, MADRS, DACOBS, and SOFAS. The correlation with the full EASE was very strong.
Conclusions: These 11 items do not necessarily relate specifically to ipseity disturbance, but the SQuEASE-11 seems to be a clinically relevant and brief supplementary first-line interview in CHR-P subjects. It may give a qualified indication of the need for a complete EASE interview, and it may also, importantly, inform treatment planning.
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Databáze: MEDLINE