Individual Difference in the Capacity of Gut Microbiota to Ferment Four Complex Carbohydrates from Normal to Overweight People: An In Vitro Study.

Autor: Yu C; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China., Ahmadi S; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China., Hu X; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China., Wu J; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China., Wu D; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China., Hou Z; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China., Pan H; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.; Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314102, China., Xiao H; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China., Ye X; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.; Zhejiang University Zhongyuan Institute, Zhengzhou 450000, China.; Shandong (Linyi) Institute of Modern Agriculture, Zhejiang University, Linyi 276000, China.; Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314102, China., Chen S; College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro Food Processing, Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang 310058, China.; Zhejiang University Zhongyuan Institute, Zhengzhou 450000, China.; Shandong (Linyi) Institute of Modern Agriculture, Zhejiang University, Linyi 276000, China.; Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing 314102, China.
Jazyk: angličtina
Zdroj: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Sep 18; Vol. 72 (37), pp. 20513-20526. Date of Electronic Publication: 2024 Sep 06.
DOI: 10.1021/acs.jafc.4c05864
Abstrakt: Pectic polysaccharides can beneficially shape the human microbiota. However, individual variability in the microbial response, especially the response between normal-weight (NW) and overweight (OW) people, is rarely understood. Therefore, we performed batch fermentation using inulin (INU), commercial pectin (CP), and pectic polysaccharides extracted from goji berry (GPP) and raspberry (RPP) by microbiota from five normal-weight (NW) and five overweight (OW) donors. The degree of specificity of fiber was negatively correlated to its fermentable rate and microbial response. Meanwhile, we found that microbiota from OW donors had a stronger fiber-degrading capacity than NW donors. The result of correlation between individual basal microbiota and the fermentable rate indicated Dialister , Megamonas , Oscillospiraceae_NK4A214 , Prevotella , Ruminococcus , and unidentified_Muribaculaceae may be the key bacteria. In summary, we highlighted a new perspective regarding the interactive relationship between different fibers and fecal microbiota from different donors that may be helpful to design fiber interventions for individuals with different microbiota.
Databáze: MEDLINE