Considerations for defining and diagnosing generalized pustular psoriasis.

Autor: Prajapati VH; Division of Dermatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.; Section of Community Pediatrics, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.; Section of Pediatric Rheumatology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.; Dermatology Research Institute, Calgary, Alberta, Canada.; Skin Health & Wellness Centre, Calgary, Alberta, Canada.; Probity Medical Research Inc., Calgary, Alberta, Canada., Lynde CW; Lynde Dermatology, Probity Medical Research, Markham and Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Gooderham MJ; SKiN Health, Probity Medical Research, Queen's University, Peterborough, Ontario, Canada., Hong HC; Division of Dermatology and Skin Science, University of British Columbia, Surrey, British Columbia, Canada.; Probity Medical Research Inc., Surrey, British Columba, Canada., Kirchhof MG; Division of Dermatology, Faculty of Medicine, University of Ottawa, and the Ottawa Hospital, Ottawa, Ontario, Canada., Lansang P; Division of Dermatology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.; Division of Dermatology, Women's College Hospital, Toronto, Ontario, Canada.; The Hospital for Sick Children, Toronto, Ontario, Canada., Ringuet J; Centre de Recherche Dermatologique du Québec (CRDQ), Québec, Quebec, Canada., Turchin I; Brunswick Dermatology Center and Probity Medical Research, Fredericton, New Brunswick, Canada.; Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada., Vender R; Division of Dermatology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Dermatrials Research Inc., Hamilton, Ontario, Canada., Yeung J; Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Probity Medical Research Inc., Toronto, Ontario, Canada., Papp KA; Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Probity Medical Research Inc., Waterloo, Ontario, Canada.; Alliance Clinical Trials, Waterloo, Ontario, Canada.
Jazyk: angličtina
Zdroj: Journal of the European Academy of Dermatology and Venereology : JEADV [J Eur Acad Dermatol Venereol] 2024 Sep 06. Date of Electronic Publication: 2024 Sep 06.
DOI: 10.1111/jdv.20310
Abstrakt: Generalized pustular psoriasis (GPP) is a rare, chronic skin disease, characterized by widespread pustules and erythema, often accompanied with systemic signs and symptoms. GPP flares occur episodically but may be protracted. Left untreated, GPP can be life-threatening. Despite being first reported over 100 years ago, definitions and diagnostic criteria for GPP have been inconsistent and varied due, in part, to its rarity and a limited understanding of its pathogenesis. As such, many patients with GPP face delays in diagnosis and subsequent treatment. This manuscript aims to increase the recognition of GPP and provide foundational considerations to aid in the definition and diagnosis of this disease.
(© 2024 The Author(s). Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd on behalf of European Academy of Dermatology and Venereology.)
Databáze: MEDLINE
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