Myosin-Inhibitor Mavacamten Acutely Enhances Cardiomyocyte Diastolic Compliance in Heart Failure With Preserved Ejection Fraction.

Autor: Almeida-Coelho J; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Portugal (J.A.-C., A.M.L.-M., A.P.L., I.F.-P., A.F.L.-M.)., Leite-Moreira AM; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Portugal (J.A.-C., A.M.L.-M., A.P.L., I.F.-P., A.F.L.-M.)., Sequeira V; Deutsches Zentrum für Herzinsuffizienz, Department of Translational Science Universitätsklinikum, Würzburg, Germany (V.S.)., Hamdani N; Division of Cardiology, Molecular and Experimental Cardiology (N.H.), Ruhr University Bochum, Germany.; Institute of Physiology (N.H.), Ruhr University Bochum, Germany., Lourenço AP; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Portugal (J.A.-C., A.M.L.-M., A.P.L., I.F.-P., A.F.L.-M.)., Falcão-Pires I; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Portugal (J.A.-C., A.M.L.-M., A.P.L., I.F.-P., A.F.L.-M.)., Leite-Moreira AF; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Portugal (J.A.-C., A.M.L.-M., A.P.L., I.F.-P., A.F.L.-M.).
Jazyk: angličtina
Zdroj: Circulation. Heart failure [Circ Heart Fail] 2024 Oct; Vol. 17 (10), pp. e011833. Date of Electronic Publication: 2024 Sep 06.
DOI: 10.1161/CIRCHEARTFAILURE.124.011833
Abstrakt: Competing Interests: Dr Sequeira has received research funding from Bristol Myers Squibb unrelated to this work. The other authors report no conflicts.
Databáze: MEDLINE