Estimation of Levels of Salivary Pyridinoline Cross-Linked Carboxyterminal Telopeptide of Type I Collagen (ICTP) in Periodontally Healthy and Diseased Patients at Various Time Intervals Before and After Periodontal Therapy.

Autor:	Agrawal P; Periodontology, Maitri College of Dentistry and Research Centre, Durg, IND., Pandit A; Periodontology, Indraprastha Dental College, Ghaziabad, IND., Malagi SK; Periodontology, Maitri College of Dentistry and Research Centre, Durg, IND., Abraham DV; Periodontics, Maitri College of Dentistry and Research Centre, Durg, IND., Vasant B; Public Health Dentistry, Maitri College of Dentistry and Research Centre, Durg, IND., Tembhurne S; Periodontology, Maitri College of Dentistry and Research Centre, Durg, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Aug 05; Vol. 16 (8), pp. e66236. Date of Electronic Publication: 2024 Aug 05 (Print Publication: 2024).
DOI:	10.7759/cureus.66236
Abstrakt:	Introduction: The bacterial plaque in the tooth-supporting tissues is the main cause of inflammatory conditions called periodontal diseases. Thus, the aim of this study is to determine the levels of intercellular matrix protein (ICTP) in patients with gingivitis and periodontitis and those who are periodontally healthy, both before and after treatment at different times. Materials and Methods: Thirty clinical parameters (bleeding on probing, probing pocket depth, and clinical attachment loss) were measured at baseline, one month, three months, and six months after the patients were divided into three groups of 60. Results: There was a significant difference between the two groups at all time intervals; the difference at one month was 34.77 (p=0.000). At three months, the difference became 31.25 (p=0.000) which increased to 36.62 (p=0.000) at six months. Conclusion: When periodontal deterioration occurs, ICTP levels are higher, and when they are reduced, periodontal health is demonstrated. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Maitri College of Dentistry and Research Centre issued approval MCDRC/2022/MAR/295. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Agrawal et al.)
Databáze:	MEDLINE
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