Facial Nerve Tractography Using Diffusion MRI: A Comparison of Acquisition b -Values and Single- and Multifiber Tracking Strategies.

Autor:	Epprecht L, Zekelman L, Reinshagen KL; Department of Radiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston MA, USA., Xie G; Department of Neurosurgery, Nuclear Industry 215 Hospital of Shaanxi Province, Xianyang, China., Norton I; Departments of Radiology., Kikinis R; Departments of Radiology., Makris N, Piccirelli M; Department of Neuroradiology, Clinical Neurocenter, University of Zurich, University Hospital of Zurich, Zurich, Switzerland., Huber A, Lee DJ; Department of Otology and Laryngology, Harvard Medical School, Boston, MA, USA., Zhang F; Departments of Radiology., O'Donnell LJ; Departments of Radiology.
Jazyk:	angličtina
Zdroj:	Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology [Otol Neurotol] 2024 Oct 01; Vol. 45 (9), pp. e647-e654. Date of Electronic Publication: 2024 Sep 05.
DOI:	10.1097/MAO.0000000000004310
Abstrakt:	Hypothesis: This study investigates the impact of different diffusion magnetic imaging (dMRI) acquisition settings and mathematical fiber models on tractography performance for depicting cranial nerve (CN) VII in healthy young adults. Background: The aim of this study is to optimize visualization of CN VII for preoperative assessment in surgeries near the nerve in the cerebellopontine angle, reducing surgery-associated complications. The study analyzes 100 CN VII in dMRI images from the Human Connectome Project, using three separate sets with different b values ( b = 1,000 s/mm 2 , b =2,000 s/mm 2 , b =3,000 s/mm 2 ) and four different tractography methods, resulting in 1,200 tractographies analyzed. Results: The results show that multifiber and free water (FW) compartment models produce significantly more streamlines than single-fiber tractography. The addition of an FW compartment significantly increases the mean streamline fractional anisotropy (FA). Expert quality ratings showed that the highest rated tractography was the 1 tensor (1T) method without FW at b values of 1,000 s/mm2. Conclusions: In this young and healthy cohort, best tractography results are obtained by using a 1T model without a FW compartment in b =1,000 diffusion MR images. The FW compartment increased the contrast between streamlines and cerebrospinal fluid (higher mean streamline FA). This finding may help ongoing research to improve CN VII tractography results in tumor cases where the nerve is often stretched and thinned by the tumor. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of Otology & Neurotology, Inc.)
Databáze:	MEDLINE
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