Atypical Presentation and Successful Management of Combined Hyperthyroidism and Adrenal Insufficiency in a Young Male.

Autor: Khalil Z; College of Medicine, October 6th university, Cairo, EGY., Hussein RE; College of Medicine, October 6th University, Cairo, EGY., Al-Abbedien EZ; Geriatrics, Bin-Seuif Hospital, Beni Suef, EGY.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Aug 04; Vol. 16 (8), pp. e66150. Date of Electronic Publication: 2024 Aug 04 (Print Publication: 2024).
DOI: 10.7759/cureus.66150
Abstrakt: This case report details the unusual presentation and successful management of a 25-year-old male diagnosed with both hyperthyroidism and adrenal insufficiency. The patient initially presented with symptoms of fatigue, weight loss, and palpitations, with no significant past medical history. Further evaluation revealed elevated thyroid hormone levels and decreased cortisol levels, confirming the diagnosis of concurrent hyperthyroidism and adrenal insufficiency. The complexity of managing these coexisting endocrine disorders required a multidisciplinary approach. Techniques utilized included detailed hormonal assays, imaging studies, and dynamic endocrine testing. The therapeutic regimen involved the administration of antithyroid medications, beta-blockers for symptom control, and glucocorticoid replacement therapy. This report underscores the importance of considering multiple endocrine disorders in patients with nonspecific systemic symptoms and highlights the need for individualized treatment plans to address the unique challenges presented by such comorbidities.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Review Board of October 6th University issued approval 2024-0274. This study was conducted in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments. The study protocol was reviewed and approved by the Institutional Review Board (IRB) of October 6th University (IRB Protocol No. 2024-0274). Written informed consent was obtained from the patient for the publication of this case report and any accompanying images. All procedures performed were in compliance with relevant laws and institutional guidelines. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Khalil et al.)
Databáze: MEDLINE