Approach to Late Noninfectious Post-Transplant Complications.
| Autor: | Alasfar S; Mayo Clinic Arizona, Division of Nephrology, Department of Medicine, Phoenix, AZ. Electronic address: Alasfar.Sami@mayo.edu., Me HM; Mayo Clinic Arizona, Division of Nephrology, Department of Medicine, Phoenix, AZ., Budhiraja P; Mayo Clinic Arizona, Division of Nephrology, Department of Medicine, Phoenix, AZ. |
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| Jazyk: | angličtina |
| Zdroj: | Advances in kidney disease and health [Adv Kidney Dis Health] 2024 Sep; Vol. 31 (5), pp. 436-449. |
| DOI: | 10.1053/j.akdh.2024.05.005 |
| Abstrakt: | The management of noninfectious complications in kidney transplant recipients includes a broad spectrum of conditions, including metabolic issues, cardiovascular diseases, and malignancies, each presenting unique challenges for nephrologists managing these patients. Unlike infectious complications, these noninfectious issues require nuanced, multidisciplinary approaches for prevention, diagnosis, and management, emphasizing the need for personalized care plans. Cardiovascular disease is particularly significant, standing as the primary cause of death post-transplantation, with recent data indicating an overtaking of cancer death rates over infections among kidney transplant recipients. The intricacies of managing these patients, influenced by the burden of kidney disease and immunosuppression, highlight the importance of a collaborative care model. Although nephrologists may not directly treat all these conditions, their understanding of the unique aspects of transplant recipients is crucial. They play a pivotal role in coordinating care with specialists such as cardiologists, endocrinologists, hematologists, and oncologists, ensuring comprehensive management that addresses these specific post-transplant complications. This review discusses the epidemiology, underlying mechanisms, clinical manifestations, and management strategies of various noninfectious complications post-kidney transplant, with a focus on cardiovascular, metabolic, oncologic, and hematologic complications. (Copyright © 2024 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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