Development, optimization and validation of automated volatile organic compound data analysis using an on-line thermal desorption gas chromatograph with dual detection and application to measurements in ambient air.

Autor: Bachelier F; Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE-CNRS), 1C, av. de la Recherche Scientifique CS 50060 - 45071, Orléans Cedex 2, France; Chromatotec, 15 rue d'Artiguelongue, Saint-Antoine 33240, France., Mascles M; Chromatotec, 15 rue d'Artiguelongue, Saint-Antoine 33240, France., McGillen MR; Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE-CNRS), 1C, av. de la Recherche Scientifique CS 50060 - 45071, Orléans Cedex 2, France., Amiet JP; Chromatotec, 15 rue d'Artiguelongue, Saint-Antoine 33240, France., Grosselin B; Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE-CNRS), 1C, av. de la Recherche Scientifique CS 50060 - 45071, Orléans Cedex 2, France., Bazin D; Chromatotec, 15 rue d'Artiguelongue, Saint-Antoine 33240, France., Daële V; Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE-CNRS), 1C, av. de la Recherche Scientifique CS 50060 - 45071, Orléans Cedex 2, France. Electronic address: veronique.daele@cnrs-orleans.fr.
Jazyk: angličtina
Zdroj: Journal of chromatography. A [J Chromatogr A] 2024 Oct 25; Vol. 1735, pp. 465327. Date of Electronic Publication: 2024 Aug 30.
DOI: 10.1016/j.chroma.2024.465327
Abstrakt: Because of their major role in indoor and outdoor air pollution, even at trace levels, VOCs are of great interest, and their monitoring requires sensitive analytical instruments. Several techniques are commonly used, such as portable sensors, Proton Transfer Reaction Mass Spectrometry (PTR-MS) and Thermal Desorption Gas Chromatography (TD-GC). The latter is widely used off- and on-line with Flame Ionization Detectors (FID) or Mass Spectrometers (MS). Given the large number of molecules detected per chromatogram, the data generated by these monitoring techniques are usually checked and reprocessed manually. This process is extremely time consuming and could result in human error. The challenge is to provide reliable results as quickly as possible. In this study, the performances of an on-line TD-GC system with dual detection FID and MS were tested. The Method Detection Limits (MDL), linearities and accuracies of 60 VOCs (alkanes, aromatics, oxygenated and halogenated) were calculated both for FID and MS detectors. The MDLs and accuracies ranged from 0.006 to 0.618 ppbv and from 77 % to 100 % for FID, and from 0.018 to 0.760 ppbv and from 80 % to 100 % for MS. Both detectors showed good complementarity and allowed the development of two programs to facilitate data analysis. These algorithms were designed to autonomously select optimal results between FID and MS detectors, and were evaluated for outdoor and indoor measurement conditions. Measuring VOCs in field campaigns is challenging, and it is anticipated that these programs could be extended to other types of dual-detector systems or for the comparison of data from different calibrated instruments.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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