Diagnosis of Graves' Disease during Treatment for Subacute Thyroiditis.
| Autor: | Yuuki M; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan., Kurasaki K; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan., Murata M; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan., Matsuda M; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan., Hata Y; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan., Horiguchi K; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan., Hamano K; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan., Nagai Y; Division of Diabetes and Endocrinology, Kanto Rosai Hospital, Japan. |
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| Jazyk: | angličtina |
| Zdroj: | Internal medicine (Tokyo, Japan) [Intern Med] 2024 Nov 01; Vol. 63 (21), pp. 2949-2952. Date of Electronic Publication: 2024 Sep 04. |
| DOI: | 10.2169/internalmedicine.3923-24 |
| Abstrakt: | The co-occurrence of subacute thyroiditis (SAT) and Graves' disease (GD) is rare. A 62-year-old Japanese man presented with shifting neck pain and elevated thyroid hormone level. The patient tested positive for thyroid-stimulating hormone receptor antibodies. Additionally, thyroid hormone levels did not decrease during treatment with prednisolone for SAT. Consequently, concurrent GD was suspected, and diagnostic assistance was obtained by confirming increased uptake on 99m Technetium thyroid scintigraphy. A genetic analysis of human leukocyte antigen (HLA) revealed genotypes associated with susceptibility to SAT (HLA-B*35:01) and GD (HLA-DPB1*05:01). Furthermore, the possibility of coronavirus disease 2019 as a related environmental factor cannot be ruled out in this case. |
| Databáze: | MEDLINE |
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