The effects of isocaloric diets derived from different lipid sources on zebrafish.

Autor: Peppi PF; Universidade Federal do Paraná - UFPR, Palotina, PR, Brasil., Faria CA; Universidade Federal do Paraná - UFPR, Palotina, PR, Brasil., Machado JPC; Universidade Federal do Paraná - UFPR, Palotina, PR, Brasil., Virote BCR; Universidade Federal de Lavras - UFLA, Departamento de Medicina Veterinária, Lavras, MG, Brasil., Carneiro WF; Universidade Federal de Lavras - UFLA, Departamento de Medicina Veterinária, Lavras, MG, Brasil., Solis-Murgas LD; Universidade Federal de Lavras - UFLA, Departamento de Medicina Veterinária, Lavras, MG, Brasil., Portz L; Universidade Federal do Paraná - UFPR, Departamento de Zootecnia, Palotina, PR, Brasil., Santos CR; Universidade de Brasília - UnB, Faculdade de Agronomia e Medicina Veterinária, Brasília, DF, Brasil., Campos LRS; Universidade de Brasília - UnB, Faculdade de Agronomia e Medicina Veterinária, Brasília, DF, Brasil., Lira GA; Universidade de Brasília - UnB, Faculdade de Agronomia e Medicina Veterinária, Brasília, DF, Brasil., Lima EMM; Universidade de Brasília - UnB, Faculdade de Agronomia e Medicina Veterinária, Brasília, DF, Brasil., Bicudo AJA; Universidade Federal do Paraná - UFPR, Departamento de Zootecnia, Palotina, PR, Brasil., Barreto-Vianna ARC; Universidade Federal do Paraná - UFPR, Palotina, PR, Brasil.
Jazyk: angličtina
Zdroj: Brazilian journal of biology = Revista brasleira de biologia [Braz J Biol] 2024 Sep 02; Vol. 84, pp. e280948. Date of Electronic Publication: 2024 Sep 02 (Print Publication: 2024).
DOI: 10.1590/1519-6984.280948
Abstrakt: Characterizing the effects of saturated fat intake on metabolic health and its changes remains a major challenge. Lipid diets, from different sources, vary widely in their physiological effects on health; therefore, it is important to consider the specific lipid source consumed. The objective of the study was to evaluate the effect of the imposition of isocaloric diets with different lipid sources in zebrafish (fish oil/pork lard). Depicting how metabolic, morphological and behavioral parameters might express themselves in these fishes. Forty adult female fishes were used for the experiment. The animals were divided into a control group (C), fed with unsaturated fatty acid diet, and a saturated fatty acid group (Sat). They received food three times a day, during the 11-week period. The results showed that animals in the Sat group had increased body weight, with a difference relative to the C group, from the third week of diet until the end of the experiment. At the end of the last week, the Sat group had a body weight 32% higher (P=0.0182) than the body weight of the control group. The consumption of a diet rich in saturated fatty acids did not generate signs related to stress and anxiety in zebrafish. There was an increase in glycemia at T60 and T120, with a statistically significant difference between the two moments. Animals in the Sat group showed an increase (P=0.0086) in hepatic steatosis compared to animals in the control group. The results obtained on the relationship between diet and metabolic changes are fundamental to ensure the understanding and appropriate treatment of these problems.
Databáze: MEDLINE